Customized Brain Stimulation to Help Finger Movement After Stroke
Tests AI-customized brain stimulation against sham stimulation for finger paralysis after stroke.
Plain-language title generated from the registry record
Registry title: AI-based Customized tDCS for Finger Motor Recovery After Subacute Stroke
Key facts
- Where
- Seoul, South KoreaSee the site
Where in South Korea
- Severance hospitalSeoul, South KoreaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- NEUROPHET
- Trial code
- NCT07491029
- Record updated
- 24 March 2026
- Original description
The goal of this clinical study is to evaluate whether AI-based customized transcranial direct current stimulation (tDCS) using MR images is more effective than sham stimulation in improving finger motor function in patients with finger paralysis caused by subacute stroke. The main questions it aims to answer are:Read full original descriptionShow less
A Multi-center, Randomized, Double-blind, Prospective, Superiority Clinical Trial to Evaluate the Safety and Effectiveness of Artificial Intelligence-based Customized Transcranial Direct Current Stimulation Using MR Images for Improving Finger Motor Function in Patients With Finger Paralysis Due to Subacute Stroke
The goal of this clinical study is to evaluate whether AI-based customized transcranial direct current stimulation (tDCS) using MR images is more effective than sham stimulation in improving finger motor function in patients with finger paralysis caused by subacute stroke. The main questions it aims to answer are:
* Does AI-based customized tDCS improve finger motor function compared with sham stimulation? * What medical problems or adverse events occur when participants receive AI-based customized tDCS?
Researchers will compare AI-based customized tDCS with sham stimulation (a look-alike stimulation that delivers no electrical current) to determine whether the intervention improves finger motor recovery in patients with subacute stroke.
Inclusion: Participants must meet all of the following criteria to be eligible for this clinical trial:; Adults aged 19 years or older; Patients with stroke confirmed by brain imaging; Subacute stroke patients within 2 weeks to 3 months after stroke onset; Patients with unilateral upper-extremity paralysis; Upper-extremity Fugl-Meyer Assessment (FMA-UE, maximum score 66) score between 20 and 56; Participants who voluntarily provide written informed consent after receiving and understanding the study procedures and requirements.
Exclusion: Use of a stimulation device similar to the investigational device or participation in a related clinical study within the past 1 year; History of a condition affecting the function of the paralyzed arm; Inability to follow instructions or complete the study due to cognitive impairment or aphasia; Evidence of delirium, confusion, or other disorders of consciousness; Presence of uncontrolled medical or surgical conditions; Severe neurological disorders associated with major psychiatric conditions (e.g., major depressive disorder, schizophrenia, bipolar disorder, or dementia); History of uncontrolled epilepsy (seizure disorder); Contraindications to transcranial direct current stimulation (tDCS), including:; Scalp disease or metal materials at the electrode attachment site; Presence of a cardiac pacemaker or cochlear implant; Participants will be excluded if they meet any of the following criteria:; Medical contraindications to MRI examination; Pregnant or breastfeeding women, or those planning pregnancy during the study period; Individuals judged by the investigator to be medically or ethically unsuitable for participation in this clinical study.