Smelling Lavender and Peppermint Oils and Pain Sensitivity in People With Migraine
Tests whether inhaling lavender or peppermint oil changes pressure pain sensitivity in adults with migraine.
Plain-language title generated from the registry record
Registry title: Evaluation of Pain Thresholds in Migraine Patients After Inhalation of Essential Oils: a Randomized Clinical Trial
Key facts
- Where
- São Paulo, BrazilSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 60 years old?
Source: NCT07493434, who can take part
Where in Brazil
- Intitute of Psychiatry- Hospital das Clínicas, University of São PauloSão Paulo, BrazilNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Sao Paulo
- Trial code
- NCT07493434
- Record updated
- 25 March 2026
- Original description
This study will test whether inhaling essential oils can change how sensitive people with migraine are to pressure pain. Participants will be allocated to inhale lavender, peppermint, a combination of both, or a control solution (distilled water with coconut oil). Each group will have 50 participants. The inhalation will last 15 minutes and will happen only once. Before and after the inhalation, we will measure how much pressure on certain areas of the head.Read full original descriptionShow less
Evaluation of Pain Thresholds in Migraine Patients After Inhalation of Essential Oils: a Randomized Clinical Trial
This study will test whether inhaling essential oils can change how sensitive people with migraine are to pressure pain. Participants will be allocated to inhale lavender, peppermint, a combination of both, or a control solution (distilled water with coconut oil). Each group will have 50 participants. The inhalation will last 15 minutes and will happen only once. Before and after the inhalation, we will measure how much pressure on certain areas of the head.
Inclusion: Adults aged 18-65 years; Diagnosis of episodic or chronic migraine according to the Internactional Classification of Headache Disorders (ICDH-3); History of migraine for at least 1 year; Ability to understand and provide informed consent; Participants currently using or not using migraine preventive medication.
Exclusion: Severe acute circulatory disorders; Diabetes melitus; Uncontrolled arterial hypertension; Known allergy or hypersensitivity to essential oils or their components; Fribromyagia; Anosmia or hyposmia; Pregnancy or breastfeeding.