Breathing Patterns Before Lung Surgery and Low Oxygen During One-Lung Ventilation
Examines whether breathing before surgery predicts low oxygen during one-lung ventilation.
Key facts
- Who runs it
- Peking University People's Hospital
- Where
- Beijing, ChinaSee the site
- Trial code
- Registry title
- Spontaneous Breathing Mode: A Risk for Hypoxemia During OLV?
- Status
- Enrolling by invitation
- People taking part
- 44 people, planned
- Started
- 15 Jul 2025
- Expected to end
- 31 Dec 2026
- Type of study
- Observational, 2 groups
- Record updated
- 27 March 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
Adults having chest surgery with one-lung ventilation, who have a body mass index (BMI) above 18.5 and below 30. The study looks at breathing before surgery and the lowest oxygen level during surgery.
- Age
- 18 years or older
- Sex
- All sexes can join
Main reasons for not taking part
- Cannot use the EIT belt before surgery
- One-lung ventilation was not carried out during surgery
The registry criteria, word for word
Show all 2 criteriaShow less
Who can take part
- Age ≥ 18 years; BMI > 18.5 and < 30; Informed consent obtained
Who cannot take part
- • Inability to use the EIT belt preoperatively; Failure to implement one-lung ventilation during surgery
Where in China
- Peking University People's HospitalBeijing, ChinaNo longer taking part
About the trial
What the trial wants to find out
Patients undergoing thoracic surgery with one-lung ventilation (OLV) are prone to hypoxemia, which is primarily attributable to pulmonary ventilation-perfusion (V/Q) mismatch. This study will preoperatively assess the distribution of pulmonary ventilation under spontaneous breathing and intraoperatively record the lowest peripheral oxygen saturation (SpO₂) during OLV. The aim is to investigate the correlation between these two parameters. The findings are expected to facilitate the prediction of hypoxemia in thoracic surgical patients undergoing OLV.
The 2 groups in the trial
- Ventilation-Matched Group
In this patient group, the dependent lung exhibited better ventilation in the lateral decubitus position during spontaneous breathing than in the supine position.
- Ventilation-Mismatched Group
In this patient group, ventilation of the dependent lung during spontaneous breathing in the lateral decubitus position was less effective than that in the supine position.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Association Between Spontaneous Breathing Mode and Hypoxemia During One-Lung Ventilation Under General Anesthesia
- Plain-language title
- Breathing Patterns Before Lung Surgery and Low Oxygen During One-Lung VentilationGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 13 November 2026.
- Record updated
- 27 March 2026