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Breathing Patterns Before Lung Surgery and Low Oxygen During One-Lung Ventilation

Examines whether breathing before surgery predicts low oxygen during one-lung ventilation.

Key facts

Who runs it
Peking University People's Hospital
Where
Beijing, ChinaSee the site
Trial code
Registry title
Spontaneous Breathing Mode: A Risk for Hypoxemia During OLV?
Status
Enrolling by invitation
People taking part
44 people, planned
Started
15 Jul 2025
Expected to end
31 Dec 2026
Type of study
Observational, 2 groups
Record updated
27 March 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

Adults having chest surgery with one-lung ventilation, who have a body mass index (BMI) above 18.5 and below 30. The study looks at breathing before surgery and the lowest oxygen level during surgery.

Age
18 years or older
Sex
All sexes can join

Main reasons for not taking part

  • Cannot use the EIT belt before surgery
  • One-lung ventilation was not carried out during surgery

The registry criteria, word for word

Show all 2 criteriaShow less

Who can take part

  • Age ≥ 18 years; BMI > 18.5 and < 30; Informed consent obtained

Who cannot take part

  • • Inability to use the EIT belt preoperatively; Failure to implement one-lung ventilation during surgery

Where in China

  • Peking University People's HospitalBeijing, ChinaNo longer taking part

About the trial

What the trial wants to find out

Patients undergoing thoracic surgery with one-lung ventilation (OLV) are prone to hypoxemia, which is primarily attributable to pulmonary ventilation-perfusion (V/Q) mismatch. This study will preoperatively assess the distribution of pulmonary ventilation under spontaneous breathing and intraoperatively record the lowest peripheral oxygen saturation (SpO₂) during OLV. The aim is to investigate the correlation between these two parameters. The findings are expected to facilitate the prediction of hypoxemia in thoracic surgical patients undergoing OLV.

The 2 groups in the trial

  • Ventilation-Matched Group

    In this patient group, the dependent lung exhibited better ventilation in the lateral decubitus position during spontaneous breathing than in the supine position.

  • Ventilation-Mismatched Group

    In this patient group, ventilation of the dependent lung during spontaneous breathing in the lateral decubitus position was less effective than that in the supine position.

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Association Between Spontaneous Breathing Mode and Hypoxemia During One-Lung Ventilation Under General Anesthesia
Plain-language title
Breathing Patterns Before Lung Surgery and Low Oxygen During One-Lung VentilationGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 13 November 2026.
Record updated
27 March 2026