Exercise Training Program for Adults With Fabry Disease
Tests a 12-week physiotherapy exercise program in adults with Fabry disease.
Plain-language title generated from the registry record
Registry title: Anderson-Fabry Disease Fitness Improvement Training
Key facts
- Where
- Prague, CzechiaSee the site
Where in Czechia
- General University HospitalPrague, CzechiaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- General University Hospital, Prague
- Trial code
- NCT07495410
- Record updated
- 21 September 2026
- Original description
This study will evaluate physical function, cardiorespiratory fitness, muscle strength, and quality of life in patients with Fabry disease and assess the effects of a 12-week physiotherapy-led exercise programme. Participants will be non-randomly assigned to an exercise intervention group or a control group receiving no study-specific exercise intervention. The intervention group will be assessed at baseline, immediately after the 12-week intervention, and 12 months after baseline. The control group will be assessed at baseline and 12 months after baseline.Read full original descriptionShow less
Anderson-Fabry Disease Fitness Improvement Training: A-FAD-FIT
This study will evaluate physical function, cardiorespiratory fitness, muscle strength, and quality of life in patients with Fabry disease and assess the effects of a 12-week physiotherapy-led exercise programme. Participants will be non-randomly assigned to an exercise intervention group or a control group receiving no study-specific exercise intervention. The intervention group will be assessed at baseline, immediately after the 12-week intervention, and 12 months after baseline. The control group will be assessed at baseline and 12 months after baseline.
Inclusion: Confirmed diagnosis of Fabry disease; Age 18 years or older; Followed at a participating clinical center; Able to understand the study procedures and provide informed consent; Clinically stable and medically suitable for exercise testing and participation in the exercise programme.
Exclusion: Acute deterioration in health status at the time of enrollment; Medical contraindication to exercise testing or exercise training; Severe comorbidity preventing safe participation in the study procedures; Inability to comply with study procedures or complete follow-up assessments.