Brief Blood Flow Interruption to Protect the Kidney During Partial Kidney Cancer Surgery
Tests ischemic preconditioning to protect kidneys in adults having partial nephrectomy for kidney cancer.
Key facts
- Who runs it
- Sun Yat-sen University
- Where
- Guangzhou, ChinaSee the site
- Trial code
- Registry title
- Ischemic Preconditioning Reduces the Severity of Acute Kidney Injury After Partial Nephrectomy
- Status
- Not yet recruiting
- People taking part
- 174 people, planned
- Started
- 1 Apr 2026
- Expected to end
- 31 Dec 2028
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Ischemic preconditioning
- NO ischemic preconditioning
- Record updated
- 27 March 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults aged 18 to 80 who are scheduled for partial nephrectomy (surgery to remove part of a kidney). It tests whether ischemic preconditioning lessens kidney injury after the operation.
- Age
- 18 to 80 years
- Sex
- All sexes can join.
- Disease stage
- People scheduled for partial nephrectomy (laparoscopic, robot-assisted or open surgery). No specific stage is named.
Main reasons for not taking part
- Cannot tolerate general anesthesia, as judged by the anesthesiologist
- Severe heart or brain blood vessel disease, uncontrolled high blood pressure or diabetes
- eGFR below 30 ml/min/1.73m²
- Horseshoe kidney or only one kidney
- Pregnant women
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Patients who are scheduled to undergo partial nephrectomy, with no specific surgical procedure limitation, including laparoscopic surgery, robot-assisted surgery, and open surgery
- Aged 18 to 80
- Possess good organ function status: sufficient organ function (based on the normal values of the clinical trial center); Blood routine test: WBC≥3.5×10\^9/L, absolute neutrophil count ≥1.5×10\^9/L, PLT≥75.0×10\^9/L, HGB≥80g/L; Liver function: Total bilirubin ≤1.5×upper limit of normal (ULN), aspartate aminotransferase (AST) and alanine aminotransferase (ALT) ≤2.5×ULN
Who cannot take part
- The anesthesiologist assesses that the patient cannot tolerate general anesthesia surgery
- Individuals with severe cardiovascular and cerebrovascular diseases, uncontrolled hypertension, and diabetes
- Estimated glomerular filtration rate (eGFR) < 30 ml/min/1.73m²
- Horseshoe kidney
- Solitary kidney
- Pregnant women
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Where in China
- 651 Dongfeng Road East, Yuexiu District, Guangzhou, P.R. China Sun Yat-sen University Cancer Center；Guangzhou, ChinaContact: Fangjian Zhou, professorNo longer taking part
About the trial
What the trial wants to find out
It is demonstrated that remote ischemic preconditioning can alleviate the degree of acute renal injury on the operated side in patients undergoing partial nephrectomy.
The 2 groups in the trial
- Experimental : Ischemic preconditioningTreatment being tested
One day before the surgery, use a sphygmomanometer to apply pressure to the patient's upper limb to 200mmHg for 5 minutes, then reduce the pressure to 0mmHg for 5 minutes, repeating this process for a total of 3 cycles. On the second day, perform a routine partial nephrectomy
Treatment: Ischemic preconditioning
- Comparator : No ischemic preconditioningExisting treatment, for comparison
Routine partial nephrectomy
Treatment: NO ischemic preconditioning
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Ischemic Preconditioning Reduces the Severity of Acute Kidney Injury After Partial Nephrectomy: a Randomized Controlled Clinical Study
- Plain-language title
- Brief Blood Flow Interruption to Protect the Kidney During Partial Kidney Cancer SurgeryGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 12 November 2026.
- Fit questions
- Built from NCT07497958, who can take part
- Record updated
- 27 March 2026