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Research on the Development, Implementation Effect and Neural Mechanism of a Physical Intervention Program for College Students With ADHD Based on the Characteristics of Balance Dysfunction

Key facts

Who runs it
Wuhan Sports University
Where
China1 site in 1 countryChoose a country to see its sites
Trial code
Status
Terminated
People taking part
130 people enrolled
Started
7 Oct 2025
Ended
15 Feb 2026
Type of study
Interventional, 3 groupsOne group gets an existing treatment, for comparison.
Treatments tested
  • Aerobic Treadmill Training
  • Progressive Balance Training
  • Cognitive-Balance Dual-Task Training
Record updated
30 March 2026
Why it stopped
The first stage of recruitment has ended because all the college students have already taken their winter vacations.

Who can take part

Age
18 years to 30 years
Sex
Women and men
Healthy volunteers
Can take part

The registry criteria, word for word

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Who can take part

  • The age range is from 18 to 30 years old, meeting the clinical diagnostic criteria for adult ADHD (DSM-5)
  • Diagnosed by a psychiatrist or clinical psychologist using standardized assessment tools (Adult ADHD Self-Rating Scale ASRS-5, Conners Adult ADHD-DIVA-5 Diagnostic Interview), and meeting the clinical diagnostic criteria for adult ADHD (DSM-5)
  • Not taking stimulant drugs to ensure that the symptom assessment is not influenced by the drugs

Who cannot take part

  • Neurological disorders: such as brain injury, epilepsy, multiple sclerosis, etc., which may affect motor functions
  • Orthopedic or musculoskeletal disorders: such as severe arthritis, muscle disorders, vestibular dysfunction, etc
  • Comorbid mental disorders: such as schizophrenia, bipolar disorder, severe depression or anxiety disorder
  • Other interfering factors: such as severe visual or hearing impairments, history of alcohol or drug dependence, etc

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

Background:

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Attention deficit/hyperactivity disorder is a common neurodevelopmental disorder. Its core symptoms and related executive function, emotional and motor coordination problems often persist into adulthood, significantly affecting the academic performance and quality of life of college students. Current drug interventions have limitations, while exercise interventions, especially training focused on balance ability, show potential in improving cognitive functions, but systematic research on this aspect for the college student population is still insufficient.

Research Objectives:

This study aims to explore the effects of different exercise intervention models on college students with attention deficit hyperactivity disorder. The main objectives include:

The system assessment focuses on the characteristics of college students with attention deficit hyperactivity disorder in terms of core symptoms, executive functions, emotional issues, and balance abilities.

Compare the effects of eight-week aerobic training, conventional balance training, and "cognitive-balance dual-task" training on improving the symptoms of attention deficit hyperactivity disorder and cognitive function.

By utilizing functional near-infrared spectroscopy technology, we aim to explore the potential brain mechanisms (such as changes in activation of the prefrontal cortex) through which exercise intervention can improve attention deficit hyperactivity disorder.

Participants:

This study will recruit college students who meet the diagnostic criteria for attention deficit hyperactivity disorder as the experimental group, and at the same time recruit healthy college students of the same age and gender as the control group.

Research Design:

This study consists of three parts:

Study 1 (Cross-sectional Comparison): To compare the baseline differences in symptoms, cognition, emotions, and balance ability between college students with attention deficit hyperactivity disorder and healthy college students.

Study Two (Randomized Controlled Trial): College students with attention deficit hyperactivity disorder were randomly assigned to three 8-week (3 times per week) intervention groups: the aerobic treadmill training group, the conventional balance training group, and the cognitive-balance dual-task training group. All participants underwent comprehensive assessments before the intervention, 4 weeks into the intervention, and 8 weeks into the intervention.

Study 3 (Exploration of Neural Mechanisms): Before and after the intervention, the functional near-infrared spectroscopy technique was used to detect the activation of the prefrontal cortex in college students with attention deficit hyperactivity disorder when they were performing cognitive tasks.

Measurement indicators:

The study will use standardized scales to assess the core symptoms of attention deficit hyperactivity disorder, anxiety, depression, self-esteem, and quality of life; use neuropsychological tasks to evaluate "cold" and "hot" executive functions; and use high-precision balance testing systems (such as the Biodex Balance Analyzer, Y Balance Test) to assess postural control and dynamic balance abilities.

Expected significance:

This study is expected to provide a scientific and effective new non-pharmacological intervention plan for adult attention deficit hyperactivity disorder, and clarify the "brain-behavior" mechanism of the synergistic enhancement of "cognitive-motor" training, providing a theoretical basis for future personalized and mechanism-driven clinical rehabilitation strategies.

The 3 groups in the trial

  • Aerobic Treadmill Training GroupExisting treatment, for comparison

    Participants receive 30-minute moderate-intensity aerobic treadmill training, 3 sessions per week for 8 weeks. Intensity is controlled at 60-75% of heart rate maximum (HRmax) and Borg RPE 12-14. Each session includes warm-up, main exercise, and cool-down.

    Treatment: Aerobic Treadmill Training

  • Balance Training GroupTreatment being tested

    Participants receive 30-minute progressive balance training, 3 sessions per week for 8 weeks. Training progresses from static stance on stable surfaces to dynamic tasks on unstable surfaces, following a structured 3-phase protocol to enhance postural control and proprioception.

    Treatment: Progressive Balance Training

  • Cognitive-Balance Dual-Task Training GroupTreatment being tested

    Participants receive 30-minute dual-task training combining progressive balance exercises with concurrent cognitive tasks (e.g., N-back, mental arithmetic, Stroop), 3 sessions per week for 8 weeks. Cognitive load increases progressively alongside balance difficulty.

    Treatment: Cognitive-Balance Dual-Task Training

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Record updated
30 March 2026