L-menthol for Breathlessness and Exercise Ability in People With Asthma
Tests L-menthol against placebo for breathlessness in adults with asthma.
Plain-language title generated from the registry record
Registry title: Efficacy of L-menthol on Breathlessness in Asthma
Key facts
- Where
- Karlskrona and Lund, SwedenSee the 2 sites
- Phase
- Phase 2
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with asthma who feel breathless and are able to cycle. It tests whether L-menthol eases breathlessness and helps exercise.
- Age
- 18 years or older
- Sex
- All sexes can join
- Disease stage
- Asthma diagnosed by a physician according to international guidelines, with an mMRC (modified Medical Research Council) breathlessness score of 1 or above
- Earlier treatment
- No hospital stay or clinical instability in the last four weeks. No extra oxygen at rest or during exercise.
Main reasons for not taking part
- Oxygen level at rest (SpO2) below 92%
- Hospital stay or clinical instability in the last four weeks
- Treatment with extra oxygen at rest or during exercise
- Expected survival shorter than six months, as judged by the investigator
- Heart failure, acute coronary artery disease, neuromuscular disease, severe psychiatric illness or a smell disorder
Read by machine on 9 November 2026.
Where in Sweden
- Blekinge Institute of TechnologyKarlskrona, SwedenContact: Jacob Sandberg, MD, PhDNot yet recruiting
- Lund University hospital and Region SkåneLund, SwedenContact: Zainab Ahmadi, MD, PhDTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Region Skane
- Trial code
- NCT07500974
- Record updated
- 19 August 2026
- Original description
The purpose of this study is to assess the effect of L-menthol on breathlessness and exercise capacity in patients with Asthma.Read full original descriptionShow less
Effect of L-menthol on Breathlessness and Exercise Capacity in Asthma: a Randomized Crossover Trial
The purpose of this study is to assess the effect of L-menthol on breathlessness and exercise capacity in patients with Asthma.
Inclusion: the subject has given written consent to participate in the study; physician diagnosis of Asthma according to international guidelines; mMRC (modified Medical Research Council) score of 1 or above; age 18 years or older; able to cycle; able to understand and talk Swedish to participate in the study procedures, as judged by the Investigators.
Exclusion: treatment with supplementary oxygen at rest or during exercise; medical conditions including congestive heart failure, acute coronary artery disease, neuromuscular diseases, severe psychiatric illness, and olfaction disorder; resting peripheral oxygen saturation (SpO2) < 92%; hospitalization or clinical instability during the last four weeks; contraindication to exercise testing in accordance with clinical practice guidelines; expected survival shorter than six months as judged by the Investigator.