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Digital messages to help people who use drugs consider HIV prevention medicine

Tests brief phone messages on stigma and PrEP in adults who use drugs.

Plain-language title generated from the registry record
Registry title: Digital PrEP Micro-Intervention for PWUD in Kazakhstan

Key facts

Where
Almaty, KazakhstanSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults in Kazakhstan who have used drugs in the past six months and are HIV-negative or do not know their HIV status. It tests short digital messages about PrEP.

Age
18 years or older
Sex
All sexes can join
Earlier treatment
Must not be taking PrEP now.
Biomarker or test result
HIV-negative or unknown HIV status, as reported by the person. No lab test is done.

Main reasons for not taking part

  • Cannot give informed consent
  • No personal mobile phone that can get Telegram or WhatsApp messages
  • Already in another PrEP behavioral intervention study

Read by machine on 12 November 2026.

Where in Kazakhstan

  • Center for Scientific and Practical InitiativesAlmaty, KazakhstanContact: Assel Terlikbayeva, MD, MS, MPH (principal investigator)No longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Trial details

Who runs it
Yale University
Trial code
NCT07508137
Record updated
8 October 2026
Original description
This study is a mixed-methods pilot designed to evaluate the feasibility, acceptability, and appropriateness of a brief digital micro-intervention aimed at reducing stigma-related barriers to pre-exposure prophylaxis (PrEP) engagement among people who use drugs (PWUD) in Kazakhstan. Participants will complete baseline and post-intervention surveys and receive structured informational content via Telegram or WhatsApp over approximately 2-3 weeks. The intervention focuses on addressing anticipated stigma, confidentiality concerns, and misinformation that may prevent PWUD from seeking PrEP services. No clinical procedures, medication provision, or biological specimen collection are involved.Read full original descriptionShow less

Digital Micro-Interventions to Reduce Stigma-Driven Barriers and Improve PrEP Readiness Among People Who Use Drugs in Kazakhstan

This study is a mixed-methods pilot designed to evaluate the feasibility, acceptability, and appropriateness of a brief digital micro-intervention aimed at reducing stigma-related barriers to pre-exposure prophylaxis (PrEP) engagement among people who use drugs (PWUD) in Kazakhstan. Participants will complete baseline and post-intervention surveys and receive structured informational content via Telegram or WhatsApp over approximately 2-3 weeks. The intervention focuses on addressing anticipated stigma, confidentiality concerns, and misinformation that may prevent PWUD from seeking PrEP services. No clinical procedures, medication provision, or biological specimen collection are involved.

Inclusion: Self-reported drug use within the past six months; HIV-negative or unknown HIV status (self-reported); Not currently taking PrEP; Able to provide informed consent; Have access to a personal mobile phone capable of receiving Telegram or WhatsApp messages.

Exclusion: Are unable to provide informed consent; Do not have access to a mobile device for digital message delivery; Are currently enrolled in another PrEP behavioral intervention study.

ClinicalTrials.gov NCT07508137