Electroacupuncture Plus Dolasetron to Prevent Nausea and Vomiting After Lung Cancer Surgery
Tests electroacupuncture with dolasetron against nausea and vomiting after lung cancer surgery.
Key facts
- Who runs it
- Shanghai Chest Hospital
- Where
- Shanghai, ChinaSee the site
- Trial code
- Registry title
- Electroacupuncture Plus 5-HT3 Receptor Inhibitor for PONV Prevention in High-Risk Patients Undergoing Thoracoscopic Lung Cancer Surgery
- Status
- Recruiting
- People taking part
- 204 people, planned
- Started
- 7 Apr 2026
- Expected to end
- 31 Dec 2026
- Type of study
- Interventional, 2 groupsOne group gets a sham (pretend) treatment, for comparison.
- Treatments tested
- Prophylactic administration of dolasetron
- Electroacupuncture
- Sham electroacupuncture
- Record updated
- 13 April 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults at high risk of nausea and vomiting after planned keyhole (thoracoscopic) lung surgery. It tests electroacupuncture together with a 5-HT3 receptor inhibitor.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Planned elective video-assisted thoracoscopic surgery (lobectomy, segmentectomy or wedge resection) for lung cancer, with ASA physical status I-III and normal lung function.
- Earlier treatment
- No acupuncture within 1 month before joining. No long-term opioid use. No previous esophageal or gastric surgery.
- Biomarker or test result
- Apfel risk score of 3 or higher; body mass index (BMI) 18-30 kg/m².
Main reasons for not taking part
- Severe heart, liver or kidney disease, or poor lung function
- Cognitive problems or psychological disorders
- Allergy to acupuncture or to the study medicines
- Infection or earlier surgery around the acupuncture sites
- Pregnant or breastfeeding women
The registry criteria, word for word
Show all 17 criteriaShow less
Who can take part
- Age ≥ 18 years
- American Society of Anesthesiologists (ASA) physical status I-III
- Body mass index (BMI) 18-30 kg/m²
- Scheduled for elective video-assisted thoracoscopic surgery (VATS) lobectomy, segmentectomy, or wedge resection
- Expected to receive postoperative opioid analgesia, with an Apfel risk score ≥ 3
- Normal pulmonary function, without severe cardiovascular, hepatic, or renal abnormalities
- No infection around the acupuncture sites
- Voluntary written informed consent provided by the subject
Who cannot take part
- History of previous esophageal or gastric surgery
- Conversion to open surgery
- Acupuncture treatment received within 1 month prior to enrollment
- Severe systemic diseases, such as cardiovascular, hepatic, or renal abnormalities, or poor pulmonary function
- Subjects with cognitive dysfunction or psychological disorders
- Hypersensitivity to acupuncture or any study medications
- Severe infection or history of surgery around the acupuncture sites
- Pregnant or lactating women
- Long-term opioid use
Where in China
- Shanghai Chest HospitalShanghai, ChinaContact: Deputy Chief PhysicianTaking people
About the trial
What the trial wants to find out
This prospective, randomized controlled study aims to evaluate the efficacy and safety of electroacupuncture combined with 5-HT3 receptor inhibitor for preventing postoperative nausea and vomiting (PONV) in high-risk patients undergoing thoracoscopic lung cancer surgery. The primary outcome is the incidence of PONV within 24 hours after surgery.
The 2 groups in the trial
- Electroacupuncture (EA) groupTreatment being tested
On the basis of receiving dolasetron and dexamethasone for preventing postoperative nausea and vomiting (PONV) during the perioperative period of video-assisted thoracoscopic surgery (VATS) for lung resection, the participants will receive electroacupuncture at 30 minutes before anesthesia induction and 4 hours after surgery.
Treatment: Prophylactic administration of dolasetron and Electroacupuncture
- sham electroacupuncture (SA) groupSham treatment, for comparison
On the basis of receiving dolasetron and dexamethasone for preventing postoperative nausea and vomiting (PONV) during the perioperative period of video-assisted thoracoscopic surgery (VATS) for lung resection, the participants will receive sham electroacupuncture at 30 minutes before anesthesia induction and 4 hours after surgery.
Treatment: Prophylactic administration of dolasetron and Sham electroacupuncture
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Electroacupuncture Combined With 5-HT3 Receptor Inhibitor for the Prevention of Postoperative Nausea and Vomiting in High-risk Patients Undergoing Thoracoscopic Surgery for Lung Cancer
- Plain-language title
- Electroacupuncture Plus Dolasetron to Prevent Nausea and Vomiting After Lung Cancer SurgeryGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 13 November 2026.
- Record updated
- 13 April 2026