Tests nicorandil for inflammation in rheumatoid arthritis
Tests nicorandil tablets for inflammation in adults with active rheumatoid arthritis.
Plain-language title generated from the registry record
Registry title: Nicorandil as Anti-inflammatory in Rheumatoid Arthritis
Key facts
- Where
- Tanta, EgyptSee the site
- Phase
- Phase 3
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 70 years old?
Source: NCT07516769, who can take part
Where in Egypt
- Tanta universityTanta, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Tanta University
- Trial code
- NCT07516769
- Record updated
- 18 June 2026
- Original description
This study aims to evaluate the possible efficacy and safety of nicorandil as anti-inflammatory in managing patients with active rheumatoid arthritis.Read full original descriptionShow less
Clinical Study Evaluating the Effect of Nicorandil as Anti-inflammatory and Immune Modulatory in Patients With Rheumatoid Arthritis
This study aims to evaluate the possible efficacy and safety of nicorandil as anti-inflammatory in managing patients with active rheumatoid arthritis.
Inclusion: Patients with active rheumatoid arthritis (not in remission) according to American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) i.e., 28 joints disease activity score (DAS-28) >2.6; Patients receiving the conventional DMARDs.
Exclusion: Patients with severe renal and hepatic dysfunction. - Patients receiving biological DMARDs; Patients receiving oral prednisolone greater than 15mg/day; Patients with heart disease (congestive heart failure, arrhythmia and ischemic heart disease), diabetes, active infection, and other illness except rheumatoid arthritis; Patients with hypersensitivity to study medications; Patients using antioxidants; Pregnant and lactating females.