Prevention and Mass Screening of TB in Prisons in Paraguay
Key facts
- Where
- Coronel Oviedo, ParaguaySee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07520448, who can take part
Where in Paraguay
- Universidad Nacional de CaaguazúCoronel Oviedo, ParaguayNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universidad Nacional de Caaguazu
- Trial code
- NCT07520448
- Record updated
- 14 April 2026
- Original description
The goal of this interventional study is to evaluate three tuberculosis (TB) screening and prevention strategies in prisons in Paraguay. The main questions it aims to answer are:Read full original descriptionShow less
Prevention and Mass Screening of TB in Prisons in Paraguay (PRESMAP-TB)
The goal of this interventional study is to evaluate three tuberculosis (TB) screening and prevention strategies in prisons in Paraguay. The main questions it aims to answer are:
* Which strategy is more effective for reducing the incidence rate of active TB? * Which strategy is more effective for reducing the TB infection rate? * Are these strategies safe, feasible, and cost-effective in prison settings?
Researchers will compare three cluster-based, non-randomized programmatic strategies implemented in three prisons. These strategies differ in the frequency of screening, the diagnostic methods used, and the approach to tuberculosis preventive therapy (TPT).
Participants will:
* undergo informed consent and clinical evaluation * receive TB screening through symptom assessment, chest digital X-ray with CAD, and rapid molecular testing, depending on site strategy * undergo IGRA testing and preventive therapy assessment, depending on the assigned strategy * be followed for 18 months, with screening rounds every 6 months or annually depending on the prison
Inclusion: Be a person deprived of liberty (PDL) residing in one of the participating penitentiary centers during the study period; Be 18 years of age or older at the time of enrollment; Be present in the penitentiary facility at the time of a screening round or enter the facility during the study period; Provide informed consent to participate in the study.
Exclusion: Are currently undergoing treatment for active tuberculosis at the time of the screening round; Have a medical condition that, in the opinion of the clinical staff, prevents the safe performance of the planned diagnostic procedures.