Two Kinds of Virtual Reality Exercise for Rehabilitation in Parkinson's Disease

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults aged 45 to 80 with idiopathic Parkinson's disease of mild to moderate severity. It compares two kinds of virtual reality rehabilitation over 12 weeks.

Age

45 to 80 years

Sex

Men and women

Disease stage

Idiopathic Parkinson's disease, mild to moderate (Hoehn & Yahr stages I-III)

Earlier treatment

Must be on conventional medical treatment that is stable at present.

Biomarker or test result

No cognitive impairment that is severe (MMSE of 24 or more).

Main reasons for not taking part

• Severe vision, hearing or movement problems not caused by Parkinson's
• Fear of virtual environments
• Illness that blocks taking part, such as advanced dementia
• Severe bone, joint or muscle conditions that limit movement
• History of epilepsy or conditions that rule out virtual reality

The registry criteria, word for word

Check if you might fit

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

• Are you between 45 and 80 years old?YesNo

What the trial wants to find out

This randomized controlled trial aims to compare the effectiveness of a Collaborative Virtual Reality Environment (CVE) and Non-Immersive Virtual Reality (NIVR) in the rehabilitation of patients with Parkinson's disease. Participants with mild to moderate disease severity will be randomly assigned to either the CVE group or the NIVR group.

The 2 groups in the trial

• CVETreatment being tested

  Participants in this arm will receive rehabilitation through a Collaborative Virtual Reality Environment (CVE), where both the patient and therapist interact simultaneously within a shared virtual space. The intervention is delivered using a head-mounted display-based system that enables real-time communication, guidance, and feedback. The rehabilitation program consists of task-specific, goal-oriented exercises targeting upper limb function, gait, balance, and functional mobility. Activities are designed to simulate real-world movements and include object manipulation, reaching tasks, and controlled walking scenarios. The therapist actively supervises and adapts the exercises during each session, ensuring appropriate progression based on patient performance. The collaborative nature of the environment facilitates increased engagement, motor learning, and adherence by incorporating interactive elements and immediate corrective feedback. The intervention follows structured progressio

  Treatment: Collaborative Virtual Environment

• NIVROther group

  Participants in this arm will undergo rehabilitation using a Non-Immersive Virtual Reality (NIVR) system delivered through a standard screen-based interface. The intervention without the use of head-mounted displays or real-time collaborative features. The rehabilitation program includes task-oriented exercises focusing on upper limb function, balance, gait-related activities, and overall functional mobility. These exercises are designed to replicate real-world movements and are performed in a structured and repetitive manner to promote motor learning. Participants will perform the activities independently with periodic supervision from a therapist. Feedback is primarily system-generated, and progression is based on predefined levels of difficulty within the software. The intervention emphasizes consistency, task specificity, and gradual progression throughout the study

  Treatment: Non-Immersive Virtual Reality (NIVR)