Exercise With Brain Stimulation to Study Movement in Parkinson's Disease
Tests exercise combined with brain stimulation in people with Parkinson's disease.
Plain-language title generated from the registry record
Registry title: Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease
Key facts
- Where
- Fuenlabrada, SpainSee the site
Where in Spain
- Center of Sport ResearchFuenlabrada, SpainTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universidad Rey Juan Carlos
- Trial code
- NCT07524400
- Record updated
- 13 April 2026
- Original description
A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on motor function will be evaluated.Read full original descriptionShow less
Effects of the Combination of Physical Exercise and Transcranial Direct Current Stimulation on Motor Function and Underlying Neurophysiological Mechanisms in Parkinson's Disease
A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on motor function will be evaluated.
Inclusion: Clinical diagnosis of idiopathic Parkinson's disease, established according to the UK Parkinson's Disease Society Brain Bank Criteria; Ability to understand and comply with study procedures; Stable antiparkinsonian medication regimen prior to study participation.
Exclusion: Current treatment with cholinesterase inhibitors; Presence or prior implantation of a deep brain stimulation (DBS) device; Significant cognitive impairment, defined as a score < 23 on the Mini-Mental State Examination (MMSE); Presence of severe cardiovascular disease, including but not limited to:; Congestive heart failure; Ischemic heart disease; Cardiac pacemaker; Uncontrolled diabetes mellitus; History of stroke or traumatic brain injury; History of seizure disorder or epilepsy; History of major orthopedic surgery that could interfere with motor performance or gait; Presence of implanted electronic devices, including cardiac pacemakers, incompatible with study procedures; Below-average premorbid intelligence, defined as a score < 40 on the Vocabulary subtest of the Wechsler Adult Intelligence Scale - Third Edition (WAIS-III); Clinically significant depression, defined as a score > 10 on the Geriatric Depression Scale (GDS-15); Orthostatic hypotension.