Reducing Blood Loss During Myomectomy:Uterine Artery Ligation Vs Pericervical Tourniquet
Key facts
- Who runs it
- Cairo University
- Where
- Egypt1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Recruiting
- People taking part
- 40 people, planned
- Started
- 10 Apr 2026
- Expected to end
- 10 Apr 2027
- Type of study
- Interventional, 2 groups
- Treatments tested
- Bilateral Uterine Artery Ligation
- Pericervical Mechanical Tourniquet Application
- Record updated
- 13 April 2026
Who can take part
- Age
- 25 years to 48 years
- Sex
- Women only
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 2 criteriaShow less
Other criteria
- Inclusion Criteria:; Female participants aged 25 to 48 years; Body mass index less than 35 kg/m²; Symptomatic uterine myomas requiring surgical treatment; Intramural myomas classified as FIGO types 3 to 6; Diagnosis confirmed by transvaginal ultrasound and/or magnetic resonance imaging; Maximum diameter of the largest myoma 20 cm or less; Scheduled for elective transabdominal myomectomy; Able and willing to provide written informed consent
- Exclusion Criteria:; Submucosal, intracavitary, pedunculated subserosal, cervical, or adnexal myomas; FIGO types 0, 1, 2, 7, or 8 myomas; History of pelvic inflammatory disease or peritonitis; Previous abdominal or pelvic surgery for non-obstetric causes; Previous uterine surgery; Use of hormonal therapy within the previous 3 months; Known bleeding disorder; Use of anticoagulant or antiplatelet therapy; Preoperative hemoglobin less than 10 g/dL; Body mass index 35 kg/m² or greater; Intraoperative conversion from myomectomy to hysterectomy
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 25 and 48 years old?
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The goal of this clinical trial is to compare two surgical techniques for reducing blood loss during transabdominal myomectomy in women with symptomatic uterine fibroids. The main question it aims to answer is whether bilateral uterine artery ligation reduces intraoperative blood loss more effectively than pericervical mechanical tourniquet application, without increasing operative complications. Researchers will compare bilateral uterine artery ligation with pericervical mechanical tourniquet application during open myomectomy to evaluate blood loss and surgical safety. Participants will undergo elective transabdominal myomectomy and will be randomly assigned to one of the two vascular control techniques before myoma enucleation.
The 2 groups in the trial
- Bilateral Uterine Artery LigationTreatment being tested
Participants assigned to this arm will undergo transabdominal myomectomy with bilateral uterine artery ligation performed before myoma enucleation. The uterine arteries will be identified bilaterally near the level of the internal cervical os and ligated using absorbable sutures to reduce uterine blood flow during surgery. Myoma enucleation and uterine repair will then be completed according to the study protocol.
- Pericervical Mechanical TourniquetTreatment being tested
Participants assigned to this arm will undergo transabdominal myomectomy with application of a pericervical mechanical tourniquet before myoma enucleation. A sterile Foley catheter will be passed around the cervico-isthmic region at the level of the internal os and tied firmly to compress the uterine vessels during surgery. The tourniquet will remain in place throughout myoma enucleation and uterine repair and will be removed after completion of hemostasis.
Treatment: Pericervical Mechanical Tourniquet Application
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Bilateral Uterine Artery Ligation Versus Pericervical Mechanical Tourniquet Application in Reducing Intraoperative Blood Loss During Transabdominal Myomectomy.
- Fit questions
- Built from NCT07526311, who can take part
- Record updated
- 13 April 2026