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Exercise Testing of Heart and Lungs in People With Lung Cancer During Treatment

Measures fitness with an exercise test in adults with lung cancer during treatment.

Plain-language title generated from the registry record
Registry title: Cardiopulmonary Exercise Testing in Lung Cancer Patients Before and During Oncological Treatment

Key facts

Where
Bialystok, PolandSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with lung cancer who are about to start standard cancer treatment and can do a supervised exercise test on a bike or treadmill.

Age
18 years or older.
Sex
All sexes can join.
Disease stage
Lung cancer confirmed by tissue testing, any stage. WHO/ECOG performance status 0-2.
Earlier treatment
Must be qualified for standard cancer treatment (surgery and/or systemic therapy).

Main reasons for not taking part

  • Unstable ischemic heart disease
  • Symptomatic cardiac arrhythmias, decompensated heart failure, or myocarditis or pericarditis
  • Active deep vein thrombosis
  • Poorly controlled asthma
  • Resting oxygen saturation ≤ 85% on room air

Read by machine on 9 November 2026.

Where in Poland

  • University Clinical Hospital in Bialystok, II Department of Pulmonology, Lung Cancer and Internal Medicine, Medical University of BialystokBialystok, PolandTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Medical University of Bialystok
Trial code
NCT07529145
Record updated
14 April 2026
Original description
Patients with lung cancer often have reduced physical fitness and coexisting health problems, which may limit their ability to tolerate oncological treatment. Standard resting lung and heart tests do not always reflect real-life physical capacity during everyday activities or physical effort.Read full original descriptionShow less

Assessment of Respiratory Parameters and Physical Performance in Patients With Lung Cancer Qualified for Oncological Treatment Before and During Therapy, With Special Consideration of Cardiovascular Risk: A Cardiopulmonary Exercise Testing Study

Patients with lung cancer often have reduced physical fitness and coexisting health problems, which may limit their ability to tolerate oncological treatment. Standard resting lung and heart tests do not always reflect real-life physical capacity during everyday activities or physical effort.

This observational study aims to assess cardiorespiratory fitness in patients with lung cancer before and during standard oncological treatment using cardiopulmonary exercise testing (CPET). CPET is a safe, supervised exercise test that provides objective information on how the heart, lungs, and muscles respond to physical effort.

Participants with WHO/ECOG performance status 0-2 will undergo CPET before treatment initiation and again after the early phase of therapy or surgery. The results may help identify patients with reduced physiological reserve and support individualized monitoring during routine clinical care.

Inclusion: Age ≥ 18 years; Histologically confirmed lung cancer (any stage); Qualified for standard oncological management (surgery and/or systemic therapy); WHO/ECOG performance status 0-2; Ability to perform cardiopulmonary exercise testing (CPET); Written informed consent.

Exclusion: Unstable ischemic heart disease; Symptomatic cardiac arrhythmias; Decompensated heart failure; Active deep vein thrombosis; Any medical condition that, in the investigator's opinion, precludes safe participation in CPET; Myocarditis or pericarditis; Suspected aortic dissection or severe aortic stenosis; Poorly controlled asthma; Resting oxygen saturation ≤ 85% on room air; Clinically relevant treatment-related adverse events above mild intensity (as applicable); Withdrawal of informed consent.

ClinicalTrials.gov NCT07529145