NCT07531732Recruiting
Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases
Study of the Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases in People With Frontotemporal Lobar Degeneration, Behavioral Variant and Alzheimer's Disease
Source: ClinicalTrials.gov · Last updated 15 Apr 2026
Brief summary (registry, in English)
This monocentric, non-interventional study (SELFSOC) investigates the relationship between self-awareness and social cognition in patients with behavioral variant frontotemporal dementia (bvFTD) and Alzheimer's disease (AD). The primary objective is to assess metacognitive efficiency related to social cognitive performance using a computerized facial emotion recognition task combined with confidence judgments. Metacognitive indices (including Mratio) will quantify the correspondence between subjective and objective performance. Thirty-four participants (17 bvFTD, 17 AD; age 50-80; MMSE ≥20) will complete two study visits involving tasks assessing emotion recognition, theory of mind, and memory.
- Status (registry)
- Recruiting
- Study type
- Observational
- Enrollment
- 34 (estimated)
- First submitted
- 8 Apr 2026
- Start date
- Apr 2026
- Primary completion date
- Dec 2027
- Lead sponsor
- Assistance Publique - Hôpitaux de Paris
- Diseases
- Frontotemporal dementia, Alzheimer disease
- NCT number
- NCT07531732
What you commit to
- Study type: Observational
- Planned participants: 34
- From Apr 2026 to the primary completion date, Dec 2027
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other illness
- Moderate to severe language disorders: Confrontation naming (DO 40 scale) ≤ 32
- Other neurological disorders (including epilepsy, Lewy body disease, vascular dementia)
- Psychiatric comorbidities (bipolar disorder, schizophrenia, current major depressive episode)
- Uncorrected visual impairment
Other
- Inability to perform computerized tasks according to the investigator's opinion
Who the study is looking for
- Diagnosis of possible or probable behavioral variant frontotemporal dementia according to the Rascovsky 2011 criteria (DLFTvc group) OR
- Diagnosis of Alzheimer's disease according to the Jack 2018 criteria, including biomarkers (MA group)
- Mini-Mental State Examination (MMSE) ≥ 20
- Age: 50-80 years
- Sufficient reading and writing proficiency in French to enable completion of the study procedures, in the investigator's opinion
Age in the registry: 50 years to 80 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Cognitive Neurology Center, Lariboisière-Fernand Widal Hospital Group, APHP Coordinator of this site? Confirm its status | Paris | France | Recruiting |
This page is information, not medical advice. Discuss any trial with your doctor.