How self-awareness relates to social understanding in frontotemporal dementia and Alzheimer's disease
Studies self-awareness and social skills in people with behavioral frontotemporal dementia or Alzheimer's disease.
Plain-language title generated from the registry record
Registry title: Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases
Key facts
- Where
- Paris, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 50 and 80 years old?
Source: NCT07531732, who can take part
Where in France
- Cognitive Neurology Center, Lariboisière-Fernand Widal Hospital Group, APHPParis, FranceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Assistance Publique - Hôpitaux de Paris
- Trial code
- NCT07531732
- Record updated
- 15 April 2026
- Original description
This monocentric, non-interventional study (SELFSOC) investigates the relationship between self-awareness and social cognition in patients with behavioral variant frontotemporal dementia (bvFTD) and Alzheimer's disease (AD).Read full original descriptionShow less
Study of the Links Between Self-awareness and Sociocognitive Processes in Neurodegenerative Diseases in People With Frontotemporal Lobar Degeneration, Behavioral Variant and Alzheimer's Disease
This monocentric, non-interventional study (SELFSOC) investigates the relationship between self-awareness and social cognition in patients with behavioral variant frontotemporal dementia (bvFTD) and Alzheimer's disease (AD).
The primary objective is to assess metacognitive efficiency related to social cognitive performance using a computerized facial emotion recognition task combined with confidence judgments. Metacognitive indices (including Mratio) will quantify the correspondence between subjective and objective performance.
Thirty-four participants (17 bvFTD, 17 AD; age 50-80; MMSE ≥20) will complete two study visits involving tasks assessing emotion recognition, theory of mind, and memory.
Inclusion: Diagnosis of possible or probable behavioral variant frontotemporal dementia according to the Rascovsky 2011 criteria (DLFTvc group) OR; Diagnosis of Alzheimer's disease according to the Jack 2018 criteria, including biomarkers (MA group); Mini-Mental State Examination (MMSE) ≥ 20; Age: 50-80 years; Sufficient reading and writing proficiency in French to enable completion of the study procedures, in the investigator's opinion.
Exclusion: Moderate to severe language disorders: Confrontation naming (DO 40 scale) ≤ 32; Other neurological disorders (including epilepsy, Lewy body disease, vascular dementia); Psychiatric comorbidities (bipolar disorder, schizophrenia, current major depressive episode); Uncorrected visual impairment; Inability to perform computerized tasks according to the investigator's opinion.