Heart ultrasound to see how the Impella pump affects both heart chambers
Uses heart ultrasound to study Impella 5.5 in adults with end-stage heart failure.
Plain-language title generated from the registry record
Registry title: Echocardiographic Assessment of the Effect of Impella on Biventricular Function
Key facts
- Where
- Rochester, United StatesSee the site
Where in United States
- University of Rochester Medical CenterRochester, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Rochester
- Trial code
- NCT07534462
- Record updated
- 9 September 2026
- Original description
The objective of this prospective observational study is to evaluate the effects of Impella 5.5 on biventricular function in adult patients with end-stage heart failure requiring temporary mechanical circulatory support. The study will assess changes in left and right ventricular global longitudinal strain and myocardial work, as well as additional echocardiographic and hemodynamic parameters. Measurements will be obtained at baseline prior to Impella implantation, immediately after device initiation, and during postoperative follow-up up to Day 14. This study involves collection of echocardiographic imaging and clinical data, including additional imaging performed for research purposes.Read full original descriptionShow less
Echocardiographic Assessment of the Effect of Impella on Biventricular Function
The objective of this prospective observational study is to evaluate the effects of Impella 5.5 on biventricular function in adult patients with end-stage heart failure requiring temporary mechanical circulatory support. The study will assess changes in left and right ventricular global longitudinal strain and myocardial work, as well as additional echocardiographic and hemodynamic parameters. Measurements will be obtained at baseline prior to Impella implantation, immediately after device initiation, and during postoperative follow-up up to Day 14. This study involves collection of echocardiographic imaging and clinical data, including additional imaging performed for research purposes.
Inclusion: Adult patients over 18 years old; Require Impella 5.5 implantation.
Exclusion: Patients' inability to provide consent for themselves (including that patients' lack of understanding the research); Any patients who are deemed at higher-than-normal risk for complications secondary to echocardiography, such as dysphagia or esophageal pathology.