"The Effect of Adductor Canal Block Performed With Postoperative Thigh Tourniquet Application on Pain After Total Knee Arthroplasty"
Key facts
- Who runs it
- Ankara Etlik City Hospital
- Where
- Türkiye1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Enrolling by invitation
- People taking part
- 60 people, planned
- Started
- 1 Mar 2026
- Planned end
- 16 Apr 2026
- Type of study
- Interventional, 2 groupsOne group gets an existing treatment, for comparison.
- Treatments tested
- Tourniquet-Assisted Adductor Canal Block (T-ACB) grou
- Standard Adductor Canal Block (S-ACB)
- Record updated
- 20 April 2026
Who can take part
- Age
- 40 years to 85 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 8 criteriaShow less
Who cannot take part
- Patients undergoing revision surgery
- Those undergoing unicompartmental (unicondylar) knee replacement, as the severity of surgical trauma differs from total replacement
- The surgical duration exceeded 180 minutes
- There was a known history of coagulopathy, peripheral neuropathy, or allergy to local anesthetics
- To ensure methodological standardization, the following cases were excluded:
- Bilateral cases, to prevent potential bias in assessing postoperative opioid consumption and pain scores
- Additionally, patients were excluded if:
- The spinal anesthesia was insufficient, requiring a conversion to general anesthesia
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 85 years old?
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
The biggest fear for patients undergoing knee replacement surgery is that persistent pain felt at the back of the knee postoperatively. While regional anesthesia is generally successful at numbing the front of the knee, managing pain in the posterior (back) area is not always easy. In this study, we tested a new method designed to alleviate pain in the back of the knee and improve patient comfort.
The 2 groups in the trial
- Standard Adductor Canal Block Group (S-ACB)Existing treatment, for comparison
Participants received a standard ultrasound-guided distal adductor canal block. During the procedure, 20 mL of 0.25% bupivacaine was injected. In this group, no tourniquet application or additional pressure modification was performed prior to the injection. The technique relied on the natural and passive distribution of the local anesthetic within the canal.
Treatment: Standard Adductor Canal Block (S-ACB)
- Tourniquet-Assisted Adductor Canal Block Group (T-ACB)Treatment being tested
Participants received an ultrasound-guided distal adductor canal block. During the procedure, a pneumatic tourniquet placed on the proximal thigh was inflated for 3-5 minutes (at a pressure of approximately 142-202 mmHg), and 20 mL of 0.25% bupivacaine was injected. Following this, the tourniquet was deflated, and a second 20 mL dose of 0.25% bupivacaine was administered. The aim of this modification was to enhance the distribution of the local anesthetic through the adductor hiatus toward the neural networks of the posterior knee (posterior fascial planes)
Treatment: Tourniquet-Assisted Adductor Canal Block (T-ACB) grou
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Fit questions
- Built from NCT07539467, who can take part
- Record updated
- 20 April 2026