A Feasibility Study on an Advanced Rehabilitative Prototype of KNEE-LOCOBOT on Knee Osteoarthritis Patients
Key facts
- Who runs it
- Tan Tock Seng Hospital
- Where
- Singapore1 site in 1 countryChoose a country to see its sites
- Trial code
- Status
- Completed
- People taking part
- 10 people enrolled
- Started
- 23 Apr 2025
- Ended
- 19 Aug 2025
- Type of study
- Interventional
- Treatments tested
- Knee Locobot
- Record updated
- 20 April 2026
Who can take part
- Age
- 21 years to 80 years
- Sex
- Women and men
- Healthy volunteers
- Cannot take part
The registry criteria, word for word
Show all 13 criteriaShow less
Who can take part
- Adults aged 21-80 years old,
- Diagnosed to have knee osteoarthritis by clinician
- Ability to understand and give consent
- Premorbid Functional Ambulation Category of 6
- Knee flexion ROM of at least 100 degrees
- Ability to sit continuously for 60 minutes
Who cannot take part
- Local factors potentially worsened by intensive robot-aided arm therapy and computer-based training: recent limb fracture, knee pain VAS >4/10, fixed knee flexion contracture >10-degree, keen flexion range of motion <100 degree
- Presence of co-existing neurological impairments causing lower limb weakness (e.g. stroke)
- Medical conditions incompatible with research participation: uncontrolled medical illnesses (hypertension or diabetes, ischaemic heart disease, congestive heart failure, bronchial asthma, severe /untreated depression, agitation, end stage renal/liver/heart/lung failure, unresolved cancers
- Any musculoskeletal condition that may limit continuous exercise duration of 30minutes
- Anticipated life expectancy of < 6 months
- Pregnant women
- Recent knee operation within past 3 month
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
Problem: Total knee replacement (TKR) surgeries are increasing due to ageing populations. Current rehabilitation has a gap - patients do unsupervised exercises at home for 2-3 weeks between hospital discharge and outpatient appointments, leading to poor compliance and complications.
Read full original descriptionShow less
Current Issues: 25% of patients don't achieve meaningful functional improvement for 6+ months, and 20% still have significant limitations after 2 years.
Proposed Solution: Deploy a robot-aided device for intensive, self-paced home rehabilitation exercises to help patients return to near-normal function within 1 month.
Goals: Improve early functional recovery, increase exercise compliance, reduce costs, and enhance long-term quality of life for knee osteoarthritis patients.
The group in the trial
- Knee LocobotTreatment being tested
Participant receive 4 weekly knee locobot training on the affected leg
Data and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Record updated
- 20 April 2026