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Reminders and planning to help people with atrial fibrillation take blood thinners

Tests text reminders and a medication calendar in adults with atrial fibrillation.

Plain-language title generated from the registry record
Registry title: Nudging for Anticoagulation Adherence in Atrial Fibrillation

Key facts

Where
Gu'ang'zhou, ChinaSee the site

Where in China

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen UniversityGu'ang'zhou, ChinaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Sun Yat-sen University
Trial code
NCT07543393
Record updated
26 June 2026
Original description
The goal of this clinical trial is to learn if a nudging intervention (using text message reminders, a medication calendar, and action planning) can help people with atrial fibrillation take their blood-thinning medication (anticoagulants) as prescribed.Read full original descriptionShow less

The Effects of Nudging Intervention in Promoting Adherence to Anticoagulation Among Patients With Atrial Fibrillation: a Randomized Controlled Trail

The goal of this clinical trial is to learn if a nudging intervention (using text message reminders, a medication calendar, and action planning) can help people with atrial fibrillation take their blood-thinning medication (anticoagulants) as prescribed.

The main questions it aims to answer are:

Does the nudging intervention improve medication adherence compared to usual care?

How does the intervention affect patients' beliefs about their medication and the automaticity of pill-taking?

Is the intervention cost-effective?

Researchers will compare participants who receive the nudging intervention with those who receive usual care.

Participants will:

Watch a short educational video about atrial fibrillation and stroke prevention

Make a personal plan to take their medication at the same time each day (for example, after breakfast)

Receive text message reminders 1 to 3 times per week, with fewer messages over time

Get a medication calendar to track daily doses

Answer a few questionnaires at the start, at 8 weeks, and at 12 weeks

Inclusion: Age ≥18 years; Diagnosed with non-valvular atrial fibrillation (AF) confirmed by medical records; Prescribed oral anticoagulants (e.g., warfarin, rivaroxaban, apixaban, dabigatran, edoxaban) for at least 3 months; Own a personal mobile phone capable of receiving SMS messages; Willing and able to provide written informed consent.

Exclusion: Severe cognitive impairment or psychiatric disorder that would preclude completion of questionnaires or adherence to the intervention; Life expectancy <6 months due to comorbid conditions; Currently enrolled in another medication adherence intervention study; Unable to read or understand Chinese (since validated Chinese scales are used).

ClinicalTrials.gov NCT07543393