Mood, Sleep and Strain in Caregivers of People With Multiple Sclerosis
Studies how caregivers' mood, sleep problems and caregiving strain relate in multiple sclerosis.
Plain-language title generated from the registry record
Registry title: Caregiver Burden in Caregivers of Patients With Multiple Sclerosis
Key facts
- Where
- Istanbul, TürkiyeSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with multiple sclerosis who are followed in physical therapy and rehabilitation clinics, together with their regular family caregivers.
- Age
- 18 to 80 years.
- Sex
- All sexes can join.
- Disease stage
- Multiple sclerosis diagnosed by a neurologist. No acute relapse or hospital stay for a flare-up in the last month.
Main reasons for not taking part
- Severe memory or thinking problems or communication problems that stop questionnaire completion
- Acute relapse or hospital stay for a flare-up within the last month
- Severe other nerve, mental health or body disease that affects the assessments
- Caregiver under 18 years old or not giving regular care
- Paid professional caregiver
Read by machine on 12 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07549048, who can take part
Where in Türkiye
- Istanbul Physical Medicine and Rehabilitation Trainig and Research HospitalIstanbul, TürkiyeContact: Büşra Ş AhıshaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
- Trial code
- NCT07549048
- Record updated
- 23 April 2026
- Original description
Individuals aged 18-80 years who have been clinically diagnosed with multiple sclerosis and their caregivers will be included in the study.Read full original descriptionShow less
The Relationship Between Mood, Insomnia Severity, and Caregiver Burden in Caregivers of Patients With Multiple Sclerosis
Individuals aged 18-80 years who have been clinically diagnosed with multiple sclerosis and their caregivers will be included in the study.
Demographic data of the patients, including age, height, weight, and comorbidities, will be recorded. Disease-specific characteristics such as disease duration, presence of incontinence, ambulation status, and presence and severity of pain will be assessed. Functional status of the patients will be evaluated using the Expanded Disability Status Scale (EDSS) and the Multiple Sclerosis Impact Scale (MSIS). Symptoms related to depression and anxiety in patients will be assessed using the Hospital Anxiety and Depression Scale (HADS).
Subsequently, caregivers of the patients will be evaluated. The severity of insomnia will be assessed using the Insomnia Severity Index (ISI). Symptoms related to anxiety and depression will be evaluated using the Hospital Anxiety and Depression Scale (HADS). Caregiver burden will be assessed using the Zarit Caregiver Burden Scale.
Inclusion: Age 18-80 years; Clinically diagnosed with multiple sclerosis by a neurologist; Being followed in the physical therapy and rehabilitation clinics during the study period; Having a primary or regular caregiver (family member); Both patient and caregiver able to read and understand Turkish and complete questionnaires; Willing to participate and provide written informed consent.
Exclusion: Severe cognitive impairment or communication problems preventing questionnaire completion; Severe comorbid neurological, psychiatric, or systemic disease affecting assessments; Caregiver with severe psychiatric, neurological, or primary sleep disorder; Caregiver <18 years old or not providing regular care; Acute relapse or hospitalization due to exacerbation within the last month; Paid professional caregiver; Refusal to participate.