Testing a heart blood test in ambulances for people with chest pain
Studies a troponin blood test in ambulances for adults with suspected heart attack.
Plain-language title generated from the registry record
Registry title: Prehospital Point-of-Care Hs-Troponin I for Rule-Out of Acute Myocardial Infarction in Patients Without ST-Segment Elevation
Key facts
- Where
- Aarhus N, DenmarkSee the site
Where in Denmark
- Prehospital Emergency Medical Services, Central Denamrk RegionAarhus N, DenmarkTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Central Denmark Region
- Trial code
- NCT07563998
- Record updated
- 2 September 2026
- Original description
People who call emergency medical services (EMS) with chest pain or other possible heart-related symptoms are often taken to hospital for further testing. However, only a small proportion of these patients are ultimately diagnosed with a serious heart condition such as a heart attack. This means that many patients undergo hospital transport and evaluation even though their risk is low.Read full original descriptionShow less
Prehospital Point-of-Care High-Sensitivity Troponin I for Rule-Out of Acute Myocardial Infarction in Suspected Non-ST-Segment Elevation Acute Coronary Syndrome: A Pilot Study
People who call emergency medical services (EMS) with chest pain or other possible heart-related symptoms are often taken to hospital for further testing. However, only a small proportion of these patients are ultimately diagnosed with a serious heart condition such as a heart attack. This means that many patients undergo hospital transport and evaluation even though their risk is low.
In hospitals, a blood test called high-sensitivity cardiac troponin is commonly used to help diagnose or rule out heart attacks. It is not yet well established whether this type of test can be used safely and effectively earlier, in the prehospital setting.
This study will investigate whether it is feasible to measure high-sensitivity troponin in the ambulance and how well the test can identify patients at low risk of serious heart conditions. A small blood sample will be taken as part of routine care and analyzed using a portable device. The test result will not be used to guide treatment or decisions during the study.
The study will assess how well the test predicts heart-related events within 30 days and how practical it is to perform the test in real-life emergency settings. The results may help guide future research on how to improve early assessment and decision-making for patients with suspected heart disease.
Inclusion: Age 18 years or older; Assessed by one of the participating EMS units equipped for POCT sampling; Presentation with symptoms suggestive of acute coronary syndrome; Planned transport to hospital for further evaluation.
Exclusion: Prior inclusion in the study within 30 days; Clinical condition requiring immediate life-saving intervention precluding study procedures; ST-segment elevation on prehospital electrocardiogram; Interhospital transport.