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Not yet recruitingEarly phase 1

AI video analysis during nose-route surgery for pituitary adenoma

Tests live AI video analysis in surgery for pituitary adenoma.

Key facts

Who runs it
University College, London
Where
United Kingdom1 site in 1 countryChoose a country to see its sites
Trial code
Registry title
AI in Endoscopic Transsphenoidal Surgery
Status
Not yet recruiting
Phase
Early phase 1
People taking part
30 people, planned
Started
1 Jun 2026
Expected to end
31 Jan 2029
Type of study
Interventional
Treatments tested
  • Live intra-op AI analysis of endoscopic video feed, with output displayed on supplementary monitor
Record updated
5 May 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults having pituitary tumour surgery through the nose with an endoscope (a thin camera tube). An AI system will analyse the surgery video live.

Age
Above 18 years old
Sex
All sexes
Disease stage
Pituitary adenoma (a pituitary gland tumour) treated with endoscopic transsphenoidal surgery (surgery through the nose)

Main reasons for not taking part

  • People younger than 18 years
  • People having surgery through the skull (transcranial surgery)
  • People having transsphenoidal surgery with a microscope instead of an endoscope
  • People unable to give consent, for example due to not understanding or mental illness

The registry criteria, word for word

Show all 7 criteriaShow less

Other criteria

  • The inclusion criteria will be:
  • Adult patients (above the age of 18 years old)
  • Undergoing endoscopic transsphenoidal surgery
  • Able to provide consent; The exclusion criteria will be:
  • Patients less than 18 years of age
  • Undergoing transcranial surgery or microscopic transsphenoidal surgery
  • Unable to provide consent e.g., cannot understand, mental illness, or later withdrawing consent

This trial has no sites in United States.

It has sites in one country. Choose a country to see its sites.

About the trial

What the trial wants to find out

This study focuses on bringing artificial intelligence into the operating room to assist with pituitary tumour surgeries performed through the nose. These procedures are technically demanding, and training new surgeons is often inconsistent. To address this, researchers at the National Hospital for Neurology and Neurosurgery are testing AI systems that "watch" surgical videos in real-time to identify anatomy, instruments, and the specific phase of the operation.

Read full original descriptionShow less

The core goal of the prospective trial is to improve education and team coordination without interfering with the surgery itself. The AI displays its analysis on tablets positioned for the surgical residents and nurses, rather than the lead surgeon. This setup allows the team to follow the procedure's progress, key anatomy and anticipate next steps without the surgeon needing to stop and explain. Because hospital internet can be unreliable, the study is prioritizing specialized hardware from NVIDIA that processes data locally. This "edge computing" approach ensures the AI is fast and doesn't require a live cloud connection to function.

This trial will assess the device feasibility (IDEAL Stage 1 study, ~6 cases), followed by early safety and system technical refinement (IDEAL 2a study, ~20-30 cases).

The group in the trial

  • Intervention ArmTreatment being tested

    Treatment: Live intra-op AI analysis of endoscopic video feed, with output displayed on supplementary monitor

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

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Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
The Application of Artificial Intelligence to Patients Undergoing Endoscopic Transsphenoidal Surgery: a Single-site Prospective Feasibility and Exploratory Study (IDEAL Stage 1 and 2a)
Plain-language title
AI video analysis during nose-route surgery for pituitary adenomaGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 15 November 2026.
Record updated
5 May 2026