Comparing Two Types of Anesthesia and Stress Levels in Weight Loss Surgery
Compares stress in adults having weight loss surgery under two anesthesia methods.
Plain-language title generated from the registry record
Registry title: Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA for Bariatric Surgery
Key facts
- Where
- Athens, GreeceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07568938, who can take part
Where in Greece
- General Hospital of Athens "G. Gennimatas"Athens, GreeceTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- G.Gennimatas General Hospital
- Trial code
- NCT07568938
- Record updated
- 6 May 2026
- Original description
The goal of this clinical trial is to compare the effects of Opioid Free Anesthesia (OFA) with and without volatile anesthetics (in this case desflurane) in patients undergoing bariatric surgery. The main question it aims to answer :Read full original descriptionShow less
Evaluation of the Stress Response in Anesthesia Use Inhalation Anesthetic (Desflurane) Versus TIVA TCI ELEVELD Model for Bariatric Surgery
The goal of this clinical trial is to compare the effects of Opioid Free Anesthesia (OFA) with and without volatile anesthetics (in this case desflurane) in patients undergoing bariatric surgery. The main question it aims to answer :
-Will there be a difference in the perioperative stress between patients receiving OFA with and without desflurane?
Participants will undergoing sleeve gastrectomy or gastric by pass, will be administered OFA with and without desflurane and blood tests (cortisole, ACTH,dopamine, PRL, adrenaline, noradrenaline, lactate) will be collected perioperatively to compare stress in the two groups.
Inclusion: Signed Informed Consent; ASA II-III; Morbid obesity confirmed diagnosis and approval for surgical treatment; Laparoscopic sleeve gastrectomy (LSG) or Gastric By pass (R-Y By pass /SASI/SADI AND one anastomosis by pass ); Preop respiratrory assessment conducted; Adequate organ and bone marrow function.
Exclusion: Patients who have received corticosteroids for durations >3 weeks at any point in their lifetime; Known allergy or hypersensitiity to any of the medications administered; Patients declining or withdrawing consent; Patients unsuitabe with regards to compliance to treatment, according to the researcher's assessment; Bradycardia, AV block, , postural hypotension; QTcF>470msec; Stop-BANG score >6; Intraoperative administration of more than 8mg of prednisolone or equivalent; Participation in other clinical trial for experimental product administered post operatively; Diagnosis of depression.