Surgery for Thumb Base Osteoarthritis: Joint Replacement vs. Trapeziectomy
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Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 80 years old?
Source: NCT07569549, who can take part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Uppsala University
- Trial code
- NCT07569549
- Record updated
- 9 October 2026
- Original description
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint osteoarthritis.Read full original descriptionShow less
BASTION - BASe of Thumb Osteoarthritis Management Non-inferiority Trial: Surgical Treatment of First Carpometacarpal Joint Osteoarthritis: A Comparison Between Joint Replacement and Trapeziectomy
The goal of this clinical trial is to learn if the surgical method with total joint arthroplasty, (TOUCH joint prosthesis), is as good as or better than the traditional surgical method, trapezectomy, to treat thumb base joint osteoarthritis.
The main questions it aims to answer are:
Does surgery with total joint arthroplasty provide better power grip and pinch grip strength compared to traditional surgery?
What is the long-term risk of complications for both methods?
Which method is more cost-effective for the healthcare system?
Researchers will compare total joint arthroplasty (TOUCH) to trapezectomy (a procedure where a bone in the thumb base is removed) to see which method provides the best results for the patient.
Participants will:
Be randomized to undergo either an operation with total joint arthroplasty or a trapezectomy.
Undergo an initial evaluation and a health economic cost analysis after one year.
Attend follow-up checkups at 2, 5, and 10 years post-surgery to evaluate long-term function and the durability of the prosthesis.
Inclusion: Age 40-80 years at inclusion; CMC-joint osteoarthritis grade 1-3 (Eaton-Littler classification); Rest pain or pain reducing hand function with indication for surgery; Insufficient relief from non-operative treatment for ≥3 months (orthosis, OTC analgesics, cortisone injection); Eligible for both prosthesis and trapezectomy per including surgeon; Non-smoker or complete smoking cessation ≥6 weeks prior to surgery.
Exclusion: Previous surgery to thumb base or STT-joint; Ongoing general chronic pain condition or other pain in the same hand predominant over the thumb base pain; Dementia or cognitive impairment; Trapezium height <7 mm on plain radiograph; Active smoker; Osteoarthritis grade 4 (Eaton-Littler).