Bladder Function in Kidney Failure Patients Awaiting Transplant
Studies bladder capacity and function in adults on dialysis awaiting kidney transplant.
Plain-language title generated from the registry record
Registry title: IMPACT OF DIALYSIS DURATION AND DIURESIS ON BLADDER CAPACITY AND COMPLIANCE IN END STAGE RENAL DISEASE PATIENTS AWAITING RENAL TRANSPLANT
Key facts
- Where
- Karachi, PakistanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07570771, who can take part
Where in Pakistan
- Sindh Institute of Urology and Transplantation (SIUT)Karachi, PakistanTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sindh Institute of Urology and Transplantation
- Trial code
- NCT07570771
- Record updated
- 6 May 2026
- Original description
Patients with end-stage renal disease (ESRD) who are on dialysis for a long time may experience bladder problems as their urine output decreases and normal bladder filling is lacking. As a result, bladder capacity may be reduced and compliance may deteriorate, which can impact the success of kidney transplantation.Read full original descriptionShow less
IMPACT OF DIALYSIS DURATION AND DIURESIS ON BLADDER CAPACITY AND COMPLIANCE IN END STAGE RENAL DISEASE PATIENTS AWAITING RENAL TRANSPLANT
Patients with end-stage renal disease (ESRD) who are on dialysis for a long time may experience bladder problems as their urine output decreases and normal bladder filling is lacking. As a result, bladder capacity may be reduced and compliance may deteriorate, which can impact the success of kidney transplantation.
Our prospective observational study is designed to investigate how dialysis duration and residual urine output (diuresis) influence bladder capacity and compliance in ESRD patients who are waiting for kidney transplantation. The adult patients undergoing regular dialysis will be assessed clinically, and they will also be subjected to laboratory tests, imaging, and urodynamic studies.
Through this study, we aim to determine the frequency of bladder malfunction and its correlation with the length of dialysis and the amount of urine excretion. The results might enhance the pre-transplant workup and offer a basis for urological post-transplantation management that could minimize complications.
Inclusion: Patients aged 18-65 years diagnosed with end-stage renal disease (ESRD); Patients on maintenance dialysis for a duration of 6 to 24 months; ESRD secondary to non-urological causes; Patients awaiting renal transplantation.
Exclusion: Patients with prior urological surgeries; Patients on medications affecting lower urinary tract function; Patients with diabetes mellitus; Patients with active urinary tract infection; Patients with neurological or systemic diseases affecting bladder function; Patients with neurogenic bladder; Patients with pre-existing lower urinary tract symptoms before dialysis.