Brain stimulation with electricity and magnets for thinking and movement problems after stroke
Tests combined electrical and magnetic brain stimulation in people after a stroke.
Plain-language title generated from the registry record
Registry title: The Effect of tDCS Combined With TMS on Cognitive Impairment and Motor Function After Stroke
Key facts
- Where
- Guangzhou, ChinaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults 30 to 80 years old who had a first stroke 1 to 6 months ago and now have problems with thinking (cognitive impairment).
- Age
- 30 to 80 years
- Sex
- All sexes can join.
- Disease stage
- First stroke, either bleeding or caused by a blocked vessel, in one side of the brain only, confirmed by CT or MRI. The stroke happened 1 to 6 months ago. Cognitive impairment after stroke is found with the MoCA scale.
- Earlier treatment
- People currently receiving non-invasive brain stimulation treatment cannot join.
Main reasons for not taking part
- Currently receiving non-invasive brain stimulation treatment
- Stroke damage in the left DLPFC brain region
- History of epilepsy, mental illness, or other neurological or mental disorders
- Any contraindication for transcranial electrical stimulation
Read by machine on 9 November 2026.
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 30 and 80 years old?
Source: NCT07573475, who can take part
Where in China
- Department of Rehabilitation Medicine, The First Affiliated Hospital, Sun Yat-sen UniversityGuangzhou, ChinaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- Ke Dong, MD
- Trial code
- NCT07573475
- Record updated
- 11 May 2026
- Original description
This clinical trial aims to investigate whether transcranial electrical stimulation (tDCS) combined with transcranial magnetic stimulation(TMS) has an impact on the cognitive and motor functions of stroke patients, and to evaluate the safety of this protocol. The main objective is to answer the following question: Can electromagnetic combined stimulation of the left Dorsolateral prefrontal lobe(DLPFC) improve the performance of working memory, motor function and cognitively motor dual tasks in stroke patients? What is its mechanism of action? Participants will undergo a combined real or sham electromagnetic stimulation of 20 minutes of tDCS and 40 seconds of TMS once a day for 7 days. Researchers will compare the effects of real stimulation with sham stimulation to see if the real stimulation can bring better results to patients. Clinical evaluations (cognitive and motor scales) and functional Near-Infrared Spectroscopy(fNIRS) were conducted before and after stimulation to record relevant brain activitiesRead full original descriptionShow less
The Effect of Transcranial Electrical Stimulation Combined With Transcranial Magnetic Stimulation on Cognitive Impairment and Motor Function After Stroke
This clinical trial aims to investigate whether transcranial electrical stimulation (tDCS) combined with transcranial magnetic stimulation(TMS) has an impact on the cognitive and motor functions of stroke patients, and to evaluate the safety of this protocol. The main objective is to answer the following question: Can electromagnetic combined stimulation of the left Dorsolateral prefrontal lobe(DLPFC) improve the performance of working memory, motor function and cognitively motor dual tasks in stroke patients? What is its mechanism of action? Participants will undergo a combined real or sham electromagnetic stimulation of 20 minutes of tDCS and 40 seconds of TMS once a day for 7 days. Researchers will compare the effects of real stimulation with sham stimulation to see if the real stimulation can bring better results to patients. Clinical evaluations (cognitive and motor scales) and functional Near-Infrared Spectroscopy(fNIRS) were conducted before and after stimulation to record relevant brain activities
Inclusion: Meeting the diagnostic criteria for hemorrhagic or ischemic stroke in the Chinese Guidelines for the Prevention and Treatment of Cerebrovascular Diseases(2nd edition), with the first onset, single hemisphere stroke, and confirmed by CT or MRI,course of diease 1-6 months; Age ranging from 30 to 80 years old; Native language is Mandarin or Cantonese; Right-handed; Diagnosed with post-stroke cognitive impairment(PSCI) by the MoCA scale; Able to cooperate in completing the speech repetition test; Normal hearing.
Exclusion: Currently receiving non-invasive brain stimulation treatment; History of epilepsy, mental illness,or other neurological or mental disorders; Lesions involving the left DLPFC brain regions; Any contraindications for transcranial electrical stimulation.