Couples counseling to support women's choice and use of HIV prevention in Uganda
Tests couples counseling to help women in Uganda choose and use HIV prevention.
Plain-language title generated from the registry record
Registry title: Improving Choice And Use Of Biomedical HIV Prevention For Women In Uganda: A Couples-based Approach
Key facts
- Where
- Kampala, UgandaSee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults in Uganda who take part in PrEP (HIV prevention medicine) services. This includes PrEP outreach staff, community board members, people at PrEP follow-up visits, CUPID tool users, PrEP providers and health officials.
- Age
- 18 years or older
- Sex
- All sexes can join.
Main reasons for not taking part
- People aged 15-17 years cannot join Aim 2
- Anyone with a condition that would prevent informed consent or make taking part unsafe
- Anyone whose condition would make the study results hard to interpret
Read by machine on 13 November 2026.
Where in Uganda
- Makerere University-Johns Hopkins University Research Collaboration MU-JHU CareKampala, UgandaContact: Dr. Brenda Gati Mirembe, MBChB, MScTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- RTI International
- Trial code
- NCT07574619
- Record updated
- 18 May 2026
- Original description
This research will evaluate the effectiveness and implementation of a couples shared decision-making intervention, CUPID (Couples United in HIV Prevention Informed Decisions), delivered in community and clinic settings to support women's pre-exposure prophylaxis (PrEP) choice and use through male partner support and shared decision-making. Through a partnership with Ministry of Health clinics already providing choices for PrEP in Uganda, the investigators will evaluate whether CUPID is effective in increasing PrEP uptake, persistence, and use among Ugandan women and assess implementation outcomes to determine whether it is acceptable and feasible to implement. If successful, CUPID will offer a community-based strategy for engaging male partners to support PrEP choice and improve HIV prevention among women and provide a scalable and sustainable intervention that will contribute to a more comprehensive approach to HIV prevention.Read full original descriptionShow less
Improving Choice And Use Of Biomedical HIV Prevention For Women In Uganda: A Couples-based Approach
This research will evaluate the effectiveness and implementation of a couples shared decision-making intervention, CUPID (Couples United in HIV Prevention Informed Decisions), delivered in community and clinic settings to support women's pre-exposure prophylaxis (PrEP) choice and use through male partner support and shared decision-making. Through a partnership with Ministry of Health clinics already providing choices for PrEP in Uganda, the investigators will evaluate whether CUPID is effective in increasing PrEP uptake, persistence, and use among Ugandan women and assess implementation outcomes to determine whether it is acceptable and feasible to implement. If successful, CUPID will offer a community-based strategy for engaging male partners to support PrEP choice and improve HIV prevention among women and provide a scalable and sustainable intervention that will contribute to a more comprehensive approach to HIV prevention.
Inclusion: All Aims:; Able and willing to provide written informed consent; Fluent in English or the dominant language spoken in the health facility's region; Aim 1:; Age ≥18 years; Meets one of the following criteria:; Performs tasks related to PrEP outreach and/or delivery in former CATALYST study areas. This may include clinic and non-clinic positions; Is a member of one of the three regional CATALYST CABs; Willing to participate in a focus group discussion; Aim 2:; Aged 18 years or older; Attending a PrEP follow-up visit; Able and willing to complete all study procedures; Aim 3:; Age ≥18 years; Meets one of the following criteria:; CUPID couples' decision tool user; A CUPID intervention provider (member of a CHT or other PrEP Provider); A provider offering PrEP choice through a health facility where CUPID is implemented; MOH or District Health Official; Willing to complete a questionnaire and participate in a qualitative interview (individual or dyadic).
Exclusion: All Aims: Participants will be excluded who have any condition that, in the opinion of the MPI or designee, would preclude informed consent, make study participation unsafe, complicate interpretation of study outcome data, or otherwise interfere with achieving the study objectives; Aim 2:.