Bedside lung blood flow imaging for people having surgery for chronic thromboembolic pulmonary hypertension
Tests electrical impedance tomography to track lung blood flow around clot-removal surgery.
Key facts
- Who runs it
- University of Sao Paulo General Hospital
- Where
- Brazil1 site in 1 countryChoose a country to see its sites
- Trial code
- Registry title
- Assessment of Pulmonary Perfusion and Hemodynamic Measurements by Electrical Impedance Tomography in Patients Undergoing Pulmonary Thromboendarterectomy.
- Status
- Recruiting
- People taking part
- 36 people, planned
- Started
- 25 Feb 2025
- Expected to end
- Dec 2026
- Type of study
- Interventional
- Treatments tested
- Electrical Impedance Tomography (EIT).
- Pulmonary Perfusion SPECT-CT.
- Pulmonary Thromboendarterectomy.
- Record updated
- 11 May 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults with chronic thromboembolic pulmonary hypertension (CTEPH), where old blood clots block lung blood vessels. They must be scheduled for surgery to remove the clots (pulmonary thromboendarterectomy) at InCor-FMUSP.
- Age
- 18 years and older
- Sex
- All sexes
- Disease stage
- Chronic thromboembolic pulmonary hypertension (CTEPH), followed at the Pulmonology Service of InCor-HCFMUSP and scheduled for pulmonary thromboendarterectomy.
Main reasons for not taking part
- Pregnancy
- Structural heart disease (atrial septal defect, ventricular septal defect or valve disease) or heart rhythm problems
- A pacemaker or other implanted electronic device
- Skin wounds on the chest where the EIT electrode belt goes
- No central vein line (central venous access) on the day of the check before surgery
The registry criteria, word for word
Show all 11 criteriaShow less
Who can take part
- Patients diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH) followed at the Pulmonology Service of InCor-HCFMUSP and scheduled for pulmonary thromboendarterectomy at InCor-FMUSP
Who cannot take part
- Structural heart disease (atrial septal defect, ventricular septal defect, or valvular heart disease)
- Cardiac arrhythmias
- Use of a cardiac pacemaker or other implantable electronic device
- Age under 18 years
- Pregnancy
- Skin lesions on the thoracic region at the site of EIT electrode belt placement
- Absence of central venous access on the day of the preoperative protocol evaluation
- Difficulty understanding the procedures to be performed
- Refusal to participate in the study (non-signing of the Informed Consent Form)
- Refusal by the attending medical team
This trial has no sites in United States.
It has sites in one country. Choose a country to see its sites.
About the trial
What the trial wants to find out
Chronic thromboembolic pulmonary hypertension (CTEPH) is a condition in which old blood clots block the blood vessels in the lungs, making it harder for the heart to pump blood through the lungs. Surgery called pulmonary thromboendarterectomy can remove these clots and improve blood flow, but doctors need reliable ways to evaluate lung blood flow before and after surgery.
Read full original descriptionShow less
This study will evaluate a bedside imaging method called electrical impedance tomography (EIT), which can measure how blood flows through different regions of the lungs without radiation or invasive procedures. Patients undergoing surgery for CTEPH will be monitored with EIT before and after surgery, and the results will be compared with standard lung perfusion imaging.
The goal of this study is to determine whether EIT can provide useful information about lung blood flow and changes after surgery, and whether it could serve as a complementary bedside tool to help monitor patients with CTEPH.
The group in the trial
- Diagnostic Imaging Ar.Treatment being tested
Patients with chronic thromboembolic pulmonary hypertension undergoing pulmonary thromboendarterectomy will be evaluated using electrical impedance tomography (EIT) for assessment of regional pulmonary perfusion in the preoperative and postoperative periods. EIT-derived perfusion indices will be analyzed and compared with imaging-based thrombus burden and pulmonary perfusion assessed by SPECT-CT.
Treatment: Electrical Impedance Tomography (EIT)., Pulmonary Perfusion SPECT-CT., and Pulmonary Thromboendarterectomy.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Assessment of Pulmonary Perfusion and Hemodynamic Measurements by Electrical Impedance Tomography in Patients Undergoing Pulmonary Thromboendarterectomy.
- Plain-language title
- Bedside lung blood flow imaging for people having surgery for chronic thromboembolic pulmonary hypertensionGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 15 November 2026.
- Record updated
- 11 May 2026