Using a one-lead heart tracing and AI to find narrowed heart arteries
Studies whether a 1-minute heart tracing can reveal narrowed coronary arteries in adults.
Plain-language title generated from the registry record
Registry title: AI-Enhanced Single-Lead ECG Screening for Coronary Stenosis
Key facts
- Where
- Moscow, RussiaSee the site
Where in Russia
- 1 University HospitalMoscow, RussiaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- I.M. Sechenov First Moscow State Medical University
- Trial code
- NCT07579624
- Record updated
- 12 May 2026
- Original description
It is a prospective, controlled, single-center, non-randomized, observational study. Two patient groups are planned for inclusion: the first - 200 patients with significant coronary artery stenosis confirmed by coronary angiography (CAG) or multislice computed tomography (MSCT) results; the second - a control group consisting of 200 patients without significant stenosis according to CAG or MSCT data.Read full original descriptionShow less
Screening for Significant Coronary Artery Stenosis Using Single-channel Electrocardiogram Analysis With Artificial Intelligence Elements
It is a prospective, controlled, single-center, non-randomized, observational study. Two patient groups are planned for inclusion: the first - 200 patients with significant coronary artery stenosis confirmed by coronary angiography (CAG) or multislice computed tomography (MSCT) results; the second - a control group consisting of 200 patients without significant stenosis according to CAG or MSCT data.
All study subjects will have a date of coronary artery imaging via CAG or MSCT with assessment of myocardial perfusion.
Stress echocardiography tests or fractional flow reserve (FFR) assessment will be conducted as indicated.
All patients included in the study will undergo ECG recording within 1 month before or after CAG or MSCT in standard lead I for 1 minute, followed by spectral analysis of the obtained data, which will be stored at the remote monitoring center of Sechenov University without being linked to the personal data of patients. A spectral analysis of the electrocardiogram will be performed using a continuous wavelet transform.
The result of this study will be the identification of ECG parameters that correlate with significant coronary artery stenosis.
Inclusion: Presence of written informed consent from the patient to participate in the study; Age 18 years and older; Outpatient visit and/or hospitalization at the research center with coronary visualization performed; Non-inclusion criteria:; Absence of sufficient data on coronary anatomy and stenosis significance; Any conditions impairing the quality of single-channel ECG recording (Parkinson's disease, essential tremor, and others); Absence of written informed consent from the patient to participate in the study.
Exclusion: Patient's unwillingness to continue participation in the study; Inability to perform full analysis of single-channel ECG digital characteristics; Refusal of coronary visualization methods for any reason.