Ultrasound Measurement of Thyroid Volume in Term Newborns
Key facts
- Who runs it
- IRCCS Ospedale San Raffaele
- Where
- Milan, ItalySee the site
- Trial code
- Status
- Recruiting
- People taking part
- 400 people, planned
- Started
- 1 May 2026
- Expected to end
- 1 May 2027
- Type of study
- Observational
- Treatments tested
- Thyroid ultrasound
- Record updated
- 10 November 2026
Who can take part
- Age
- 1 day to 7 days
- Sex
- Women and men
- Healthy volunteers
- Can take part
The registry criteria, word for word
Show all 6 criteriaShow less
Who can take part
- Healthy full term newborns (born between 37 and 42 weeks of gestation, with no antennal issue or complications at birth)
- Consent obtained by parent(s) or legal guardian(s)
Who cannot take part
- Congenital malformations
- TSH abnormalities in neonatal screening
- Pregnancy not carried out in Italy, due to different iodine status
- Inability or unwillingness of the parent(s) or legal guardian(s) to provide informed consent or to comply with study procedures
Where in Italy
- IRCCS Ospedale San RaffaeleMilan, ItalyContact: Maria Cristina Vigone, MDTaking people
About the trial
What the trial wants to find out
First, to date, no data are available on the thyroid volume of full-term newborns in Italy, making it essential to conduct studies to establish reference values for normality. This allows these values to be correlated with maternal and fetal variability, providing a scientific basis for better understanding thyroid development in the first days of life. Thyroid ultrasound is useful for supplementing newborn screening for congenital hypothyroidism, helping to identify early abnormalities. Furthermore, thyroid volume is a sensitive indicator of iodine intake, essential for assessing the population's iodine nutritional status. It is equally valuable for studying and monitoring the effects of maternal and environmental factors, for which thyroid volume itself serves as a marker. Having normal values allows for a more precise comparison and contextualization of data from children with pathologies, who undergo ultrasound for pathological screening. In summary, these regulatory references improve the diagnosis, prevention, and management of neonatal thyroid dysfunction, contributing to a more informed public health.
The group in the trial
- Healthy term newborns
Healthy, born between 37 to 42 weeks of gestational age
Treatment: Thyroid ultrasound
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Ultrasound Measurement of Thyroid Volume in Term Newborns : a Single-centre Cross Sectional Observational Study
- Record updated
- 10 November 2026