Digital self-management support for people with heart failure in Pakistan
Tests a digital self-management program to help adults with heart failure take their medicines.
Plain-language title generated from the registry record
Registry title: SUPPORT-HEART-PK: Effectiveness, Implementation, and Cost-Effectiveness of a Theory-Based, RE-AIM-Informed Digital Self-Management Intervention for Heart Failure in Pakistan-A Hybrid Type 1 Effectiveness-Implementation Randomized Controlled Trial
Key facts
- Where
- Karachi, PakistanSee the site
Where in Pakistan
- Civil Hospital Karachi, Dr. Ruth K. M. Pfau Civil Hospital KarachiKarachi, PakistanNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Universiti Putra Malaysia
- Trial code
- NCT07580508
- Record updated
- 30 September 2026
- Original description
Medication non-adherence leads to recurrent admissions, worsening symptoms, poor quality of life, and increased healthcare costs in an already overburdened health system. Existing adherence interventions in Pakistan are limited, mostly educational, and rarely guided by behavioural theory, implementation science, or economic evaluation.Read full original descriptionShow less
SUPPORT-HEART-PK: Effectiveness, Implementation, and Economic Evaluation of a RE-AIM-Informed, Theory-Based Digital Self-Management Intervention for Heart Failure Management-A Hybrid Type 1 Effectiveness-Implementation Randomized Controlled Trial
Medication non-adherence leads to recurrent admissions, worsening symptoms, poor quality of life, and increased healthcare costs in an already overburdened health system. Existing adherence interventions in Pakistan are limited, mostly educational, and rarely guided by behavioural theory, implementation science, or economic evaluation.
Therefore, a culturally appropriate, RE-AIM-informed autonomy-competence intervention is needed to improve medication adherence and quality of life among heart failure patients in Pakistan, while also assessing implementation feasibility and cost-effectiveness for future scale-up.
Inclusion: Age ≥18 years; Diagnosed heart failure for at least 6 months; Prescribed ≥2 heart failure medications; Documented medication non-adherence; Able to provide informed consent; Access to a smartphone.
Exclusion: Severe psychiatric illness; Terminal illness; Severe cognitive impairment; End-stage renal disease; Participation in another intervention trial.