Effect of High-Intensity Laser Therapy on Femoral Cartilage in Knee Osteoarthritis
Key facts
- Where
- Lahore, PakistanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 40 and 60 years old?
Source: NCT07584603, who can take part
Where in Pakistan
- London Aesthetics and Rejuvenation CenterLahore, PakistanContact: Ayesha Malik, MSNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University of Lahore
- Trial code
- NCT07584603
- Record updated
- 13 May 2026
- Original description
This clinical trial will evaluate the effects of High-Intensity Laser Therapy (HILT) on femoral cartilage thickness and other clinical outcomes in people with knee osteoarthritis. Participants aged 40 to 60 years with grade II or III knee osteoarthritis will be randomly assigned to receive either HILT plus conventional physiotherapy or conventional physiotherapy alone. Both groups will receive 12 treatment sessions on alternate days for 4 weeks. The study will assess changes in cartilage thickness using ultrasound, as well as improvements in pain, knee movement, muscle strength, and daily function. Findings from this research may help improve physiotherapy treatment strategies for patients with knee osteoarthritis.Read full original descriptionShow less
The Role of High-intensity Laser Therapy on Femoral Cartilage Thickness in Patients With Knee Osteoarthritis
This clinical trial will evaluate the effects of High-Intensity Laser Therapy (HILT) on femoral cartilage thickness and other clinical outcomes in people with knee osteoarthritis. Participants aged 40 to 60 years with grade II or III knee osteoarthritis will be randomly assigned to receive either HILT plus conventional physiotherapy or conventional physiotherapy alone. Both groups will receive 12 treatment sessions on alternate days for 4 weeks. The study will assess changes in cartilage thickness using ultrasound, as well as improvements in pain, knee movement, muscle strength, and daily function. Findings from this research may help improve physiotherapy treatment strategies for patients with knee osteoarthritis.
Inclusion: Male and female participants aged 40-60 years; Diagnosed with knee osteoarthritis (Kellgren-Lawrence grade II or III); Knee pain for at least 3 months; Visual Analogue Scale (VAS) score ≥ 3; Willing to provide written informed consent and comply with treatment and follow-up schedule.
Exclusion: History of knee surgery or traumatic knee injury; History of cancer or psychiatric illness; Cognitive disorders (e.g., Parkinson's disease, Alzheimer's disease); Severe comorbidities limiting exercise (e.g., severe COPD, heart failure, cerebrovascular event); Inflammatory arthritis (e.g., gout, psoriatic arthritis); Hip or ankle joint disability; Intra-articular knee injection within the past 3 months.