A lifestyle program for people living with multiple sclerosis
Tests a 12-week program of food, exercise, sleep and stress in adults with MS.
Plain-language title generated from the registry record
Registry title: Healthy Eating and Active Living for People Living With Multiple Sclerosis (HEAL MS): A Lifestyle Program for People With Multiple Sclerosis
Key facts
- Where
- Abu Dhabi, United Arab EmiratesSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 50 years old?
Source: NCT07589062, who can take part
Where in United Arab Emirates
- Yas ClinicAbu Dhabi, United Arab EmiratesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- New York University Abu Dhabi
- Trial code
- NCT07589062
- Record updated
- 15 May 2026
- Original description
The goal of this clinical trial is to learn whether a structured lifestyle program can improve health and wellbeing in people living with multiple sclerosis (MS). The program focuses on four areas: nutrition, physical activity, sleep, and stress management. The study will also examine how lifestyle changes affect biological markers related to inflammation, metabolism, and immune function.Read full original descriptionShow less
HEAL MS: A Culturally Adapted Lifestyle Medicine Intervention Targeting Metabolic and Immune Dysregulation in Multiple Sclerosis Using Multi-Omics Profiling
The goal of this clinical trial is to learn whether a structured lifestyle program can improve health and wellbeing in people living with multiple sclerosis (MS). The program focuses on four areas: nutrition, physical activity, sleep, and stress management. The study will also examine how lifestyle changes affect biological markers related to inflammation, metabolism, and immune function.
The main questions the study aims to answer are:
Can a 12-week lifestyle program improve fatigue, physical function, sleep, and quality of life in people with MS? Do lifestyle changes influence biological markers related to inflammation, metabolism, and mitochondrial function?
Participants will first complete a 12-week observation period to measure their usual lifestyle and health. After this, they will take part in the 12-week HEAL MS lifestyle program.
Participants will:
Attend four assessment visits at Yas Clinic (baseline, before the intervention, after the intervention, and three months later) Participate in two supervised online exercise sessions per week during the 12-week program Follow a structured nutrition plan, with meals provided during the first two weeks Use a mobile application to log daily habits related to exercise, nutrition, sleep, and stress Complete questionnaires and physical tests and provide blood, saliva, and stool samples during assessment visits
Researchers will analyze these data to understand whether lifestyle interventions can support symptom management and overall health in people living with MS.
Inclusion: Confirmed MS diagnosis (McDonald criteria); EDSS score ≤ 6.5 (i.e., ambulatory with or without assistance); Stable disease-modifying therapy for ≥ 3 months; Age 18-50; Proficiency in English or Arabic; Clearance to participate in a structured exercise program; Ability to walk, sit and stand independently, and perform light-to-moderate movement patterns, even with modifications; Ability and digital literacy to interact with the bilingual HEAL MS mobile app and; Access to a computer for participation in online sessions.
Exclusion: Concurrent enrollment in another lifestyle intervention; Significant cognitive impairment affecting app use and comprehension of the intervention; Unmanaged psychiatric disorders; Other immune-related or chronic inflammatory or metabolic diseases; MS relapse within the past 3 months; Pregnancy or planned pregnancy.