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Sonazoid CEUS for Early HCC Surveillance

Key facts

Where
Tianjin, ChinaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT07590284, who can take part

Where in China

  • Tianjin Third Central HospitalTianjin, ChinaNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Tianjin Third Central Hospital
Trial code
NCT07590284
Record updated
15 May 2026
Original description
This study is a multicenter, prospective study. In this study, enrolled subjects are cirrhotic patients of any etiology. The US and Sonazoid CEUS monitoring strategy was performed for cirrhotic patients: US and AFP joint with Sonazoid CEUS every 4 to 6 months, and combined CECT/CEMRI every 12 months.Read full original descriptionShow less

A Multicenter, Prospective Study of Sonazoid CEUS for Early HCC Surveillance in a High-risk Population

This study is a multicenter, prospective study. In this study, enrolled subjects are cirrhotic patients of any etiology. The US and Sonazoid CEUS monitoring strategy was performed for cirrhotic patients: US and AFP joint with Sonazoid CEUS every 4 to 6 months, and combined CECT/CEMRI every 12 months.

Inclusion: Cirrhotic patients diagnosed clinically or radiologically due to any etiology (patients with cirrhosis due to congenital fibrosis and patients with cirrhosis due to vascular causes were excluded); Age 18-80 years old; Able to receive regular imaging, including US, CEUS, and CECT or CEMRI or EOB-MRI, according to the diagnostic and treatment procedures; Obtained informed consent from the patient.

Exclusion: Patients with known hypersensitivity to enhanced imaging contrast agents; Patients with severe cardiac, pulmonary or renal insufficiency that precludes CECT or CEMRI or EOB-MRI; Patients with egg or egg-product allergy, or with severe right-to-left cardiac shunt or intrapulmonary shunt; Patients with pathologic or enhanced imaging of established HCC who have not undergone curative treatment; Lactating and pregnant women; Those who are not suitable for enrollment as assessed by the investigator.

ClinicalTrials.gov NCT07590284