Two breathing measures for predicting ventilator weaning success in people with COPD
Compares two breathing measures for predicting who can come off a ventilator, in COPD.
Plain-language title generated from the registry record
Registry title: D-RSBI Versus RSBI for Predicting Weaning Success in COPD Patients
Key facts
- Where
- Sohag, EgyptSee the site
Where in Egypt
- Sohag University HospitalSohag, EgyptTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Sohag University
- Trial code
- NCT07590362
- Record updated
- 15 May 2026
- Original description
This prospective observational cohort study aims to compare the predictive accuracy of diaphragmatic rapid shallow breathing index (D-RSBI) versus traditional rapid shallow breathing index (RSBI) for predicting weaning success from invasive mechanical ventilation in COPD patients. Diaphragmatic ultrasound measurements will be performed during spontaneous breathing trials, and patients will be followed for 72 hours after extubation to assess weaning outcomes.Read full original descriptionShow less
Diaphragmatic Rapid Shallow Breathing Index (D-RSBI) Versus Traditional Rapid Shallow Breathing Index (RSBI) for Prediction of Weaning Success From Mechanical Ventilation in COPD Patients
This prospective observational cohort study aims to compare the predictive accuracy of diaphragmatic rapid shallow breathing index (D-RSBI) versus traditional rapid shallow breathing index (RSBI) for predicting weaning success from invasive mechanical ventilation in COPD patients. Diaphragmatic ultrasound measurements will be performed during spontaneous breathing trials, and patients will be followed for 72 hours after extubation to assess weaning outcomes.
Inclusion: Mechanically ventilated COPD patients fulfilling standard weaning readiness criteria; Invasive mechanical ventilation for more than 24 hours before spontaneous breathing trial; Hemodynamically stable without significant vasopressor support; Adequate oxygenation with FiO2 ≤ 0.5 and PEEP ≤ 8 cmH2O ; Preserved mental status and ability to initiate spontaneous breathing; Successful tolerance of spontaneous breathing trial conducted on CPAP mode with pressure support ≤ 8 cmH2O.
Exclusion: Recent major thoracic surgery; Neuromuscular disease, phrenic nerve palsy, or diaphragmatic paralysis; Refusal of consent; Large pneumothorax or pathology interfering with ultrasound assessment; Terminal extubation; Poor sonographic window despite repeated attempts.