NCT07592637Not yet recruiting
Lung Disease and FLNA Mutations
Prevalence and Characteristics of Lung Disease Associated With FLNA Mutations: a Multicenter Cross-sectional Study
Source: ClinicalTrials.gov · Last updated 26 May 2026
Brief summary (registry, in English)
Some sparse scientific data support the hypothesis that otherwise unexplained emphysema may be associated with FLNA variants. This transversal multicentric study aimed to describe the frequency of emphysema in patients carrying an FLNA variation. Patients with FLNA variations who accept the study will benefit from a chest physician's clinical examination, respiratory function tests, a cardiac ultrasound and a chest scan. The primary endpoint is to describe emphysema's frequency in patients carrying FLNA variation. The other objectives are to describe emphysema's features in these patients, the prevalence of pulmonary hypertension and to describe their lung function abnormalities. The final goal is to confirm the association between unexplained emphysema and FLNA mutation.
- Status (registry)
- Not yet recruiting
- Study type
- Interventional
- Enrollment
- 70 (estimated)
- First submitted
- 22 Apr 2026
- Start date
- Sept 2026
- Primary completion date
- Mar 2029
- Lead sponsor
- University Hospital, Lille
- NCT number
- NCT07592637
What you commit to
- Study type: Interventional
- Planned participants: 70
- From Sept 2026 to the primary completion date, Mar 2029
- 1 site in 1 country
- Visits and tests: ask the trial team, the registry does not list them
Built from the registry fields of ClinicalTrials.gov. It describes the study, not your situation.
Who cannot take part
Copied verbatim from ClinicalTrials.gov and grouped by topic. Only the trial team decides who can take part.
Other
- Patient refused or unable to give informed consent
- Administrative reasons: inability to receive information, inability to participate in the entire study, lack of coverage by the social security system,
- Pregnant or breastfeeding women
- Patient under guardianship
- Persons deprived of liberty
Who the study is looking for
- Patient with an FLNA mutation (or gene alteration)
- Patient who has given written consent to participate in the trial
- Socially insured patient
- Patient willing to comply with all study procedures and duration
Age in the registry: 18 years to 99 years · Sex: All · Does not accept healthy volunteers
Sites (1)
Sites in registry order. Pick your city on the disease page to sort them by distance.
| Site | City | Country | Site status |
|---|---|---|---|
| Lille University Hospital Coordinator of this site? Confirm its status | Lille | France | Unknown status |
This page is information, not medical advice. Discuss any trial with your doctor.