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Spinal cord stimulation plus medicine for pain after a stroke

Tests short-term spinal cord stimulation added to medicine in adults with post-stroke pain.

Plain-language title generated from the registry record
Registry title: Treatment of Post-Stroke Central Pain

Key facts

Where
Nanchong, ChinaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with long-lasting nerve pain that began after a stroke. It tests short-term spinal cord stimulation plus medicines against medicines alone.

Age
18 years or older
Sex
All sexes can join
Disease stage
Central post-stroke pain meeting IASP criteria, with a stroke confirmed by CT or MRI. Pain with nerve-type features, not explained by other causes, lasting 3 months or longer. Baseline pain score (NRS) of 4 or more.

Main reasons for not taking part

  • Chronic pain before the stroke
  • Severe memory or thinking problems that prevent pain rating (MMSE below 15)
  • Reasons spinal cord stimulation cannot be used, such as clotting disorders, active infection or mental illness that prevents cooperation
  • Cancer or other severe organ disease with expected survival under 1 year

Read by machine on 9 November 2026.

Where in China

  • Nanchong Central HospitalNanchong, ChinaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Nanchong Central Hospital
Trial code
NCT07593313
Record updated
18 May 2026
Original description
To evaluate the short-term analgesic efficacy of stSCS combined with pharmacotherapy compared with pharmacotherapy alone in patients with CPSP, measured by Numerical Rating Scale (NRS) score immediately after treatment.Read full original descriptionShow less

Efficacy and Safety of Short-Term Spinal Cord Stimulation Combined With Pharmacotherapy for Central Post-Stroke Pain: A Single-Center, Randomized, Controlled Trial

To evaluate the short-term analgesic efficacy of stSCS combined with pharmacotherapy compared with pharmacotherapy alone in patients with CPSP, measured by Numerical Rating Scale (NRS) score immediately after treatment.

Inclusion: Diagnosis of central post-stroke pain (CPSP) according to the International Association for the Study of Pain (IASP) criteria; Clear history of stroke confirmed by cranial CT or MRI; Pain occurring after stroke and distributed in body parts corresponding to central nervous system injury; Pain with neuropathic characteristics (e.g., burning sensation, electric shock sensation, needle prick sensation); Pain not explained by other causes; Age ≥ 18 years; Pain duration ≥ 3 months; Baseline pain Numerical Rating Scale (NRS) score ≥ 4 points; Complete clinical data with follow-up time ≥ 6 months.

Exclusion: History of chronic pain before stroke; Severe cognitive impairment that prevents cooperation with pain assessment (Mini-Mental State Examination, MMSE < 15 points); Contraindications to spinal cord stimulation (SCS), such as coagulation disorders, active infections, or mental diseases that prevent cooperation; Malignant tumors or other severe organic diseases with expected survival < 1 year.

ClinicalTrials.gov NCT07593313