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Spinal cord stimulation plus medicine for pain after a stroke

Tests short-term spinal cord stimulation added to medicine in adults with post-stroke pain.

Plain-language title generated from the registry record
Registry title: Treatment of Post-Stroke Central Pain

Key facts

Where
Nanchong, ChinaSee the site

Where in China

  • Nanchong Central HospitalNanchong, ChinaTaking people

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Trial details

Who runs it
Nanchong Central Hospital
Trial code
NCT07593313
Record updated
18 May 2026
Original description
To evaluate the short-term analgesic efficacy of stSCS combined with pharmacotherapy compared with pharmacotherapy alone in patients with CPSP, measured by Numerical Rating Scale (NRS) score immediately after treatment.Read full original descriptionShow less

Efficacy and Safety of Short-Term Spinal Cord Stimulation Combined With Pharmacotherapy for Central Post-Stroke Pain: A Single-Center, Randomized, Controlled Trial

To evaluate the short-term analgesic efficacy of stSCS combined with pharmacotherapy compared with pharmacotherapy alone in patients with CPSP, measured by Numerical Rating Scale (NRS) score immediately after treatment.

Inclusion: Diagnosis of central post-stroke pain (CPSP) according to the International Association for the Study of Pain (IASP) criteria; Clear history of stroke confirmed by cranial CT or MRI; Pain occurring after stroke and distributed in body parts corresponding to central nervous system injury; Pain with neuropathic characteristics (e.g., burning sensation, electric shock sensation, needle prick sensation); Pain not explained by other causes; Age ≥ 18 years; Pain duration ≥ 3 months; Baseline pain Numerical Rating Scale (NRS) score ≥ 4 points; Complete clinical data with follow-up time ≥ 6 months.

Exclusion: History of chronic pain before stroke; Severe cognitive impairment that prevents cooperation with pain assessment (Mini-Mental State Examination, MMSE < 15 points); Contraindications to spinal cord stimulation (SCS), such as coagulation disorders, active infections, or mental diseases that prevent cooperation; Malignant tumors or other severe organic diseases with expected survival < 1 year.

ClinicalTrials.gov NCT07593313