Following PrEP users and testing a decision tool for HIV prevention in clinics
Follows people using PrEP and tests a tool to guide PrEP decisions.
Plain-language title generated from the registry record
Registry title: DYnamic decisioN Support for IntegrAting PrEP in Clinics for Young People in Alabama and Botswana
Key facts
- Where
- Bontleng, BotswanaSee the site
Where in Botswana
- Princess Marina HospitalBontleng, BotswanaNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Alabama at Birmingham
- Trial code
- NCT07597824
- Record updated
- 14 October 2026
- Original description
This study evaluates strategies to improve access to HIV prevention through the integration of pre-exposure prophylaxis (PrEP) into existing healthcare settings, rather than limiting delivery to specialty clinics. The study addresses barriers to PrEP uptake, including limited awareness, stigma, and restricted access, and recognizes that availability alone may not ensure initiation or sustained use.Read full original descriptionShow less
DYnamic decisioN Support for IntegrAting PrEP in Clinics for Young People in Alabama and Botswana
This study evaluates strategies to improve access to HIV prevention through the integration of pre-exposure prophylaxis (PrEP) into existing healthcare settings, rather than limiting delivery to specialty clinics. The study addresses barriers to PrEP uptake, including limited awareness, stigma, and restricted access, and recognizes that availability alone may not ensure initiation or sustained use.
The study includes two components. First, a longitudinal cohort of current PrEP users will be followed to assess changes in access, preferences, and PrEP use over time in real-world settings. Second, a dynamic decision-support toolkit will be developed and evaluated to support patients and providers in PrEP-related decision-making. The toolkit will include patient- and provider-facing components to support clinical decision-making, improve risk understanding, and facilitate integration of PrEP into routine healthcare. The toolkit will be refined and beta-tested in selected healthcare facilities in Botswana and Alabama.
Group 1; Inclusion for Alabama site:; 18 years of age or older; Currently using or eligible for PrEP; Inclusion for Botswana site:; 18 years of age or older; Participated in the parent Tshireletso study in Botswana; Exclusion for both sites:; Under the age of 18; HIV positive; Group 2; Inclusion for both sites:; 18 years of age or older; Currently working as PrEP providers or clinic administrators at outpatient clinics; Exclusion for both sites:; Under the age of 18; Group 3; Inclusion for both sites:; 18 years of age or older; Currently working as policy makers or program leaders at outpatient clinics; Exclusion for both sites:; Under the age of 18.