How Removing Extra Fluid Affects Sleep Apnea in Heart Failure
Looks at sleep apnea before and after fluid removal in hospitalized heart failure patients.
Plain-language title generated from the registry record
Registry title: The Impact of Volume Overload on Obstructive Sleep Apnea in Patients With Congestive Heart Failure
Key facts
- Where
- Jerusalem, IsraelSee the site
Where in Israel
- Shaare Zedek Medical CenterJerusalem, IsraelTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Itshak Amsalem
- Trial code
- NCT07601724
- Record updated
- 22 May 2026
- Original description
The goal of this observational study is to learn how removing extra fluid from the body (diuresis) affects sleep apnea in adults hospitalized with heart failure.Read full original descriptionShow less
The Impact of Volume Overload on Obstructive Sleep Apnea in Patients With Congestive Heart Failure
The goal of this observational study is to learn how removing extra fluid from the body (diuresis) affects sleep apnea in adults hospitalized with heart failure.
The main questions it aims to answer are:
Does sleep apnea severity improve after fluid removal? Is the improvement in sleep apnea related to the amount of fluid removed? Do changes in neck size reflect changes in sleep apnea severity?
Participants admitted to the hospital with heart failure and fluid overload will take part in this study.
Participants will:
Use a wearable sleep monitoring device (WatchPAT) on the first night of hospitalization Use the device again after fluid removal, when the treating cardiologist determines that the patient is no longer fluid overloaded Have their neck circumference measured before and after fluid removal Have their weight and fluid balance recorded during hospitalization Have routine blood tests and clinical assessments as part of standard care
Researchers will compare each participant's results before and after fluid removal to see if sleep apnea improves and whether these changes are linked to fluid removal and changes in neck circumference.
Inclusion: Adults aged 18 years or older; Hospitalized with decompensated heart failure and clinical evidence of fluid overload; Diagnosis of heart failure (reduced or preserved ejection fraction); Clinically indicated for diuretic therapy; Able to undergo sleep apnea assessment using the WatchPAT device; Able to provide informed consent.
Exclusion: Current treatment with continuous positive airway pressure (CPAP); Acute respiratory failure requiring mechanical ventilation; Conditions preventing proper use of the WatchPAT device (e.g., severe hand or finger injury); Known central sleep apnea as the predominant sleep-disordered breathing type; Hemodynamic instability precluding participation; Pregnancy.