Heart Rate Patterns for Spotting Sleep Apnea in People With High Blood Pressure
Studies heart rate patterns and overnight sleep testing in adults with high blood pressure.
Plain-language title generated from the registry record
Registry title: Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension
Key facts
- Where
- Kaohsiung City, TaiwanSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07603583, who can take part
Where in Taiwan
- Kaohsiung Armed Forces General HospitalKaohsiung City, TaiwanTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Kaohsiung Armed Forces General Hospital
- Trial code
- NCT07603583
- Record updated
- 22 May 2026
- Original description
This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function.Read full original descriptionShow less
The Exploration of the Relationship Between Hypertension and Sleep Apnea Through Heart Rate Variability, and the Subsequent Investigation of Non-pharmacological and Pharmacological Treatments
This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function.
Hypertensive patients at high risk for OSA will undergo 24-hour Holter electrocardiogram monitoring to assess HRV parameters, along with overnight polysomnography (PSG) to determine OSA severity. The study will analyze the association between HRV indices and the apnea-hypopnea index (AHI), and develop predictive models using machine learning techniques.
In addition, patients diagnosed with OSA will be followed after treatment, and changes in HRV and blood pressure will be evaluated to assess treatment effects and autonomic function recovery.
The results of this study may provide a cost-effective and clinically applicable approach for early detection, risk stratification, and management of OSA in patients with hypertension.
Inclusion: Age 18 to 65 years; Diagnosed hypertension or resistant hypertension; STOP-Bang score ≥3 indicating high risk of obstructive sleep apnea; Willing and able to provide informed consent.
Exclusion: Unstable medical condition that may interfere with study participation; Refusal to undergo HRV monitoring or polysomnography; Inability to comply with study procedures.