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Taking people in Hong KongNo phase

Checking how well the CIDI 5.0 interview identifies depression, anxiety and PTSD

Compares the CIDI 5.0 interview with a clinical interview for depression, anxiety and PTSD.

Plain-language title generated from the registry record
Registry title: Validation of the CIDI 5.0 Against the SCID-5 for Lifetime Mental Disorders

Key facts

Where
Hong Kong, Hong KongSee the site

Where in Hong Kong

  • The University of Hong KongHong Kong, Hong KongTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
The University of Hong Kong
Trial code
NCT07604753
Record updated
22 May 2026
Original description
The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders. Earlier versions, such as the CIDI 3.0, demonstrated acceptable individual-level concordance with clinical assessments based on DSM-IV criteria (Haro et al. 2006). The latest iteration (CIDI 5.0) has been updated to operationalize DSM-5 criteria.Read full original descriptionShow less

Validity of the World Health Organization CIDI 5.0 for Assessing Lifetime Prevalence of Mental Disorders: A Clinical Reappraisal Study Using the SCID-5

The World Health Organization Composite International Diagnostic Interview (CIDI) is a fully structured diagnostic tool designed for lay interviewers to assess the prevalence of mental and substance use disorders. Earlier versions, such as the CIDI 3.0, demonstrated acceptable individual-level concordance with clinical assessments based on DSM-IV criteria (Haro et al. 2006). The latest iteration (CIDI 5.0) has been updated to operationalize DSM-5 criteria.

Recent evidence from a large-scale, community-based national study in Qatar suggests that under DSM-5 criteria (Khaled et al. 2024), after recalibration, the CIDI 5.0 maintains high specificity (91.9% for MDD, 94.7% for GAD, and 85.5% for PTSD). Sensitivity suggested CIDI diagnoses aligned closely with clinical "gold standard" diagnoses (51.5% for MDD, 50.7% for GAD, and 77.3% for PTSD). Despite the evidence from Qatar, there remains a lack of evidence regarding the validity of the CIDI 5.0 in population-based studies.

Therefore, this study aims to evaluate the diagnostic validity of the CIDI 5.0 for Lifetime MDD, GAD, and PTSD, using the Structured Clinical Interview for DSM-5 (SCID-5) as the definitive clinical gold standard.

Inclusion: All household members aged 18 years old and over are randomly sampled from the Census and Statistics Department List of Quarters; Live in the address sampled from the Census and Statistics Department List of Quarters; Reside in Hong Kong for at least six months in the past year; Able to read and communicate in Chinese or English; Without linguistic or cognitive difficulties.

Exclusion: Domestic workers.

ClinicalTrials.gov NCT07604753