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Isoinertial Training to Improve Strength in People With COPD

Tests isoinertial training against usual rehabilitation in adults with COPD aged 50 to 80.

Plain-language title generated from the registry record
Registry title: Isoinertial Training in Patients With COPD

Key facts

Where
Bogotá and Ibague, ColombiaSee the 2 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 50 and 80 years old?

Source: NCT07605117, who can take part

Where in Colombia

  • Universidad Manuela BeltránBogotá, ColombiaTaking people
  • Pulsar Unidad de Neumologia y Rehabilitación PulmonarIbague, ColombiaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Universidad Manuela Beltrán
Trial code
NCT07605117
Record updated
29 May 2026
Original description
Isoinertial training is emerging as a potentially effective strategy to improve strength and functionality in older people diagnosed with chronic obstructive pulmonary disease (COPD), due to its influence on muscle mass and neuromuscular efficiency. COPD is characterized by systemic alterations, including peripheral muscle dysfunction; which contributes to patient functional limitation, and reduces patients' quality of life. Isoinertial training may improve the physiological response to effort, and also promote functional performance in this population. Hence, the aim of this study is to evaluate the effect of an isoinertial training program on muscle strength and functional capacity in patients with COPD during an 8-week intervention.Read full original descriptionShow less

Effect of Isoinertial Training on Muscle Strength and Functional Capacity in Patients With Chronic Obstructive Pulmonary Disease (COPD): A Randomized Controlled Clinical Trial

Isoinertial training is emerging as a potentially effective strategy to improve strength and functionality in older people diagnosed with chronic obstructive pulmonary disease (COPD), due to its influence on muscle mass and neuromuscular efficiency. COPD is characterized by systemic alterations, including peripheral muscle dysfunction; which contributes to patient functional limitation, and reduces patients' quality of life. Isoinertial training may improve the physiological response to effort, and also promote functional performance in this population. Hence, the aim of this study is to evaluate the effect of an isoinertial training program on muscle strength and functional capacity in patients with COPD during an 8-week intervention.

Inclusion: People between 50 - 80 years of age diagnosed with moderate or severe COPD; No acute exacerbations in the last 4 weeks; Sufficient functional capacity to exercise; Signed informed consent.

Exclusion: Presence of neurological, musculoskeletal, or cardiovascular diseases that significantly limit exercise performance or compromise participant safety; including uncontrolled hypertension, recent myocardial infarction, unstable angina, severe osteoarthritis, stroke sequelae, or Parkinson's disease; Cognitive disorders; Contraindications to exercise participation according to medical evaluation; Recent surgeries in the past 3 months; Simultaneous participation in other exercise programs.

ClinicalTrials.gov NCT07605117