Early rhythm control for people with atrial fibrillation and tricuspid regurgitation
Compares early rhythm control with usual care in people with atrial fibrillation and tricuspid regurgitation.
Plain-language title generated from the registry record
Registry title: Efficacy of Early Rhythm Control in AF With TR Patients
Key facts
- Where
- Seoul, South KoreaSee the site
Where in South Korea
- Samsung Medical CenterSeoul, South KoreaTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Samsung Medical Center
- Trial code
- NCT07607093
- Record updated
- 29 May 2026
- Original description
Atrial fibrillation is frequently accompanied by tricuspid regurgitation and may contribute to right atrial and tricuspid annular remodeling, leading to progression of tricuspid regurgitation and adverse clinical outcomes. However, whether early rhythm control improves prognosis in patients with atrial fibrillation and tricuspid regurgitation remains unclear. This study will compare early rhythm control with usual care in these patients, using a composite outcome of cardiac death, heart failure admission, stroke, and tricuspid valve surgery.Read full original descriptionShow less
Efficacy of Early Rhythm Control in AF With TR Patients
Atrial fibrillation is frequently accompanied by tricuspid regurgitation and may contribute to right atrial and tricuspid annular remodeling, leading to progression of tricuspid regurgitation and adverse clinical outcomes. However, whether early rhythm control improves prognosis in patients with atrial fibrillation and tricuspid regurgitation remains unclear. This study will compare early rhythm control with usual care in these patients, using a composite outcome of cardiac death, heart failure admission, stroke, and tricuspid valve surgery.
Inclusion: Patients with concomitant atrial fibrillation and tricuspid regurgitation.
Exclusion: Patients with CIED implantation prior to the diagnosis of tricuspid regurgitation; Patients diagnosed with TR only after the initiation of rhythm control therapy for AF; Patients with a history of valvular surgery; Patients with congenital heart disease; Patients with primary pulmonary hypertension.