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Following older rural adults with atrial fibrillation to screen for heart failure

Screens older rural adults with atrial fibrillation for heart failure and follows them over time.

Plain-language title generated from the registry record
Registry title: Construction of a Cohort of Elderly Patients With Atrial Fibrillation in Rural China

Key facts

Where
Taizhou, ChinaSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 65 and 80 years old?

Source: NCT07611084, who can take part

Where in China

  • Department of CardiologyTaizhou, ChinaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
Jiangsu Taizhou People's Hospital
Trial code
NCT07611084
Record updated
28 May 2026
Original description
Atrial fibrillation (AF) is a common arrhythmia in aging populations and is strongly associated with an increased risk of heart failure (HF) and adverse cardiovascular outcomes. However, early detection of HF among patients with AF remain inadequate in rural settings. This study aims to screen for HF among older adults with AF in rural China and to conduct long-term follow-up in order to observe the disease progression in patients with AF.Read full original descriptionShow less

Construction of a Cohort of Elderly Patients With Atrial Fibrillation in Rural China

Atrial fibrillation (AF) is a common arrhythmia in aging populations and is strongly associated with an increased risk of heart failure (HF) and adverse cardiovascular outcomes. However, early detection of HF among patients with AF remain inadequate in rural settings. This study aims to screen for HF among older adults with AF in rural China and to conduct long-term follow-up in order to observe the disease progression in patients with AF.

This study will recruit at least 2,500 elderly individuals aged between 65 and 80 years, with confirmed diagnoses of AF, residing in rural areas. Participants will undergo HF screening using NT-proBNP testing and echocardiographic assessment. Additionally, data will be collected on electrocardiographic signals, seismocardiography, voice, and demographic characteristics. Following data collection, participants will be followed up every three months to monitor the incidence and progression of HF as well as the occurrence of adverse cardiovascular events.

Inclusion: Permanent residents with local household registration in rural China; Aged 65-80 years; Electrocardiogram confirmation of AF or possession of a diagnostic certificate for AF issued by a specialist; Willing to participate in HF screening; Ability to understand the study procedures and provide written informed consent.

Exclusion: Severe renal insufficiency (Ccr < 30ml/min) or ongoing dialysis treatment; Cardiac insufficiency secondary to correctable causes, including hyperthyroid heart disease, anemic heart disease, or uncorrected congenital heart disease; Chronic obstructive pulmonary disease complicated by type II respiratory failure; Special populations, including patients with mental illnesses; Expected life expectancy of less than 3 months; Indications for pacemaker implantation without having undergone implantation.

ClinicalTrials.gov NCT07611084