Home exercise program with remote monitoring for people with a heart pump
Tests a 12-week home exercise program in adults with a heart pump.
Plain-language title generated from the registry record
Registry title: REACTION-VAD Trial: Remote Exercise Training Via Telemedicine in Patients With Long-Term Ventricular Assist Devices
Key facts
- Where
- A Coruña, Barcelona, Madrid, Majadahonda, Salamanca, Santiago de Compostela, and Seville, SpainSee the 10 sites
Where in Spain
- Complejo Hospitalario Universitario de A CoruñaA Coruña, SpainNo longer taking part
- Hospital Clinic de BarcelonaBarcelona, SpainNo longer taking part
- Hospital Universitari de BellvitgeBarcelona, SpainNo longer taking part
- Hospital 12 de OctubreMadrid, SpainNo longer taking part
- Hospital Clínico San CarlosMadrid, SpainNo longer taking part
- Hospital Ramón y CajalMadrid, SpainNo longer taking part
- Hospital Puerta de HierroMajadahonda, SpainNo longer taking part
- Hospital Universitario De SalamancaSalamanca, SpainNo longer taking part
- Complejo Hospitalario Universitario Santiago de CompostelaSantiago de Compostela, SpainNo longer taking part
- Hospital Virgen Del RocioSeville, SpainNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Puerta de Hierro University Hospital
- Trial code
- NCT07611188
- Record updated
- 28 May 2026
- Original description
Current international guidelines recommend that patients with a heart pump (left ventricular assist device, LVAD) participate in supervised exercise cardiac rehabilitation programs. However, not all patients with a heart pump are able to attend to a supervised program on a daily basis.Read full original descriptionShow less
Efficacy and Safety of a Remote Conditioning Program in Patients Supported With a Ventricular Assist Device: THE RE-ACTION-VAD TRIAL.
Current international guidelines recommend that patients with a heart pump (left ventricular assist device, LVAD) participate in supervised exercise cardiac rehabilitation programs. However, not all patients with a heart pump are able to attend to a supervised program on a daily basis.
The goal of this clinical trial is to determine whether a home-based exercise program helps patients with a heart pump improve their exercise capacity and quality of life, guided by telemedicine tools including a mobile app, smartwatch, and remote medical checkups. The study will also provide information about the safety of this program by monitoring for any issues or symptoms during home activity.
The trial aims to answer the following questions:
* Does a 12-week remote exercise program improve patients' exercise capacity? This will be measured using the 6-minute walk test and a cardiopulmonary exercise test. * Is it safe for patients to follow this exercise plan at home while being monitored through a mobile app and smartwatch? * Does the program improve quality of life and reduce feelings of anxiety or depression? This will be assessed using widely validated questionnaires, such as the Kansas City Cardiomyopathy Questionnaire.
Researchers will compare the remote exercise program to standard care, which usually does not include exercise for patients who are unable to attend the hospital daily.
Participants will:
* Join the study voluntarily after signing a consent form. * Be randomly assigned, with a 50% chance of being in either the exercise group (following a structured plan with a mobile app) or the usual care group (receiving general written advice), to see which approach works best for recovery. * Follow a 12-week home-based routine if in the exercise group, including warm-up routine, walking or cycling, respiratory exercises, and light strength training, all supported by the mobile app, smartwatch, and professional monitoring. * Visit the hospital three times over six months for medical checkups, including walking and exercise tests, blood analyses, and questionnaires about physical and emotional health.
Inclusion: Recent LVAD Implantation (<6 months); Clinical stability (defined as meeting all of the following criteria): discharge from the LVAD implantation hospitalization, absence of inotropic medication, hemoglobin >9 g/dL, and no active infection; Inability to participate in a supervised rehabilitation program (due to lack of availability, or inability because geographical reasons).
Exclusion: Prior Participation in a Supervised Rehabilitation Program (after the LVAD implantation); Functional Inability to Perform Cardiopulmonary Exercise Testing.