Virtual reality cycling exercise for motivation in adults with neurological conditions and frailty
Compares cycling with and without virtual reality for motivation in adults with neurological conditions.
Plain-language title generated from the registry record
Registry title: Evaluation of the Impact of Virtual Park on Training Motivation in Adult Patients
Key facts
- Where
- Bari, Costa Masnaga, Milan, Montescano, Pavia, Pisa, and Telese Terme, ItalySee the 7 sites
Where in Italy
- Istituti a Carattere Scientifico Maugeri BariBari, ItalyNo longer taking part
- Centro di Riabilitazione Villa BerettaCosta Masnaga, ItalyNo longer taking part
- Istituti a Carattere Scientifico Maugeri Milano CamaldoliMilan, ItalyNo longer taking part
- Istituti a Carattere Scientifico Maugeri MontescanoMontescano, ItalyNo longer taking part
- Istituti a Carattere Scientifico Maugeri PaviaPavia, ItalyNo longer taking part
- Università di PisaPisa, ItalyNo longer taking part
- Istituti a Carattere Scientifico Maugeri TeleseTelese Terme, ItalyNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Marta Mondellini
- Trial code
- NCT07616050
- Record updated
- 29 May 2026
- Original description
The purpose of this clinical study is to evaluate the feasibility, usability, and motivational impact of VirtualPark, a virtual reality-based dual-task rehabilitation system, in adults with neurological and age-related conditions.Read full original descriptionShow less
Evaluation of the Impact of a Rehabilitation Intervention Based on Cycling With Virtual Park on Training Motivation in Adult Patients
The purpose of this clinical study is to evaluate the feasibility, usability, and motivational impact of VirtualPark, a virtual reality-based dual-task rehabilitation system, in adults with neurological and age-related conditions.
VirtualPark is a virtual reality application designed to deliver cognitive exercises during cycling training using a commercially available ergometer (THERA-Trainer Tigo). The system integrates physical and cognitive tasks in simulated real-life environments.
The intervention integrates motor and cognitive training tasks targeting domains such as attention, inhibition, working memory, and navigation.
This is a prospective, multicenter, randomized, cross-over pilot study. It will compare cycling training performed with and without virtual reality. Participants will complete both intervention conditions over a 4-week period separated by a wash-out phase with standard rehabilitation activities. The order of conditions will be randomized.
The study will assess motivation during rehabilitation training, usability and user experience of the system, as well as exploratory effects on cognitive and motor performance, functional abilities, perceived exertion, and safety.
The study will enroll adult participants (≥18 years) with conditions such as stroke, Parkinson's disease, multiple sclerosis, amyotrophic lateral sclerosis, mild cognitive impairment, spinal cord injury, and frail older adults.
Inclusion: Informed consent to the study; subjects > 18 years and <85 years; diagnosis of MCI according to the criteria of the Diagnostic and Statistical Manual of Mental Disorders VTh Edition (DSM V TR American Psychological Association 2013); detection of ischemic stroke within 6 months preceding the study, frail elderly subjects (Gobbens RJ et al. 2010); subjects affected by idiopathic Parkinson's disease according to the MDS-PD criteria (Postuma et al., 2015); subjects affected by possible, probable and definite ALS according to the revised El Escorial criteria (Brooks Br, et al. 2000); subjects affected by MS according to the McDonald criteria (2017) with disability measured with the EDSS (Expanded Disability Status Scale) <= 8; patients with spinal cord injury of different etiology with incomplete spinal cord injury, AIS (ASIA impairment scale) grade C and D, MMSE >18; subjects naïve to the use of the RV; no therapeutic changes or rehabilitation interventions in the month prior to inclusion in the study; no ongoing behavioral disorders.
Exclusion: Other concomitant neurological pathologies in addition to the one under study; presence of visual disturbances that do not allow access to the experimental virtual reality protocol; presence of impaired cardiorespiratory function or other organic instabilities that contraindicate ergometer training; severe osteoporosis.