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Taking people in CanadaPhase 2

Tests EVO756 for preventing migraine in adults

Tests EVO756 against placebo to prevent migraine in adults aged 18 to 64.

Plain-language title generated from the registry record
Registry title: Study of EVO756 in Adults With Migraine

Key facts

Where
Québec, CanadaSee the site
Phase
Phase 2

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with migraine who have tried preventive migraine treatments that did not work. It tests EVO756 against placebo.

Age
18 to under 65 years (18 to 64 years).
Sex
All sexes can join.
Disease stage
Migraine with or without aura, as defined by ICHD-3 criteria.
Earlier treatment
Must have had no success with earlier preventive migraine treatments. Must not be using a migraine preventive treatment now.

Main reasons for not taking part

  • Difficulty telling migraine apart from other headache types
  • Other primary headache disorders
  • Use of certain medications
  • Any clinically significant medical, psychiatric, neurological, cardiovascular or laboratory abnormalities

Read by machine on 13 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 64 years old?

Source: NCT07616128, who can take part

Where in Canada

  • Centre de Recherche St-LouisQuébec, CanadaContact: EVO756-MIG001 Research SiteTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
Evommune, Inc.
Trial code
NCT07616128
Record updated
4 November 2026
Original description
This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.Read full original descriptionShow less

A Randomized, Double-Blind, Placebo Controlled Study Evaluating the Efficacy and Safety of EVO756 for the Prevention of Migraine in Adults

This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.

Inclusion: Adults aged 18 to <65 years; Migraine with or without aura, per ICHD-3 criteria; History of failure with prior preventive migraine treatments; Not currently using migraine preventive therapy.

Exclusion: Use of certain medications; Difficulty distinguishing migraine from other headache types or presence of other primary headache disorders; Any clinically significant medical, psychiatric, neurological, cardiovascular, or laboratory abnormalities.

ClinicalTrials.gov NCT07616128